Horizons in Neuroscience Research. Volume 47

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Andres Costa and Eugenio Villalba (Editors)

Series: Horizons in Neuroscience Research
BISAC: MED057000

This volume includes nine chapters that describe recent advancements in neuroscience research. Chapter One studies the correlation between genes and violence. Chapter Two focuses on the effect of specific Central Nervous System (CNS) drugs and substances on neurotransmission of sleep, particularly at the Rapid Eye Movement (REM) stage. Chapter Three explores the potential of social cognition as a therapeutic target in schizophrenia. Chapter Four describes therapy methods for language neurorehabilitation in a few patients with brain injuries. Chapter Five provides current knowledge about in vitro toxicology studies in neuroblastoma cells for the treatment of neuroblastoma. Chapter Six reviews evidence supporting the bidirectional relationship between kynurenine pathway alterations, induction of activated microglia, and subsequent release of pro-inflammatory cytokines in Huntington’s Disease patients and models. Chapter Seven presents the course of early neurorehabilitation treatment with emphasis on optimizing balance assessment in clinical practice, identifying impairments, informing treatment planning, and maximizing the effectiveness of exercise interventions to improve balance and reduce falls in patients after cerebellopontine angle tumor resection. Chapter Eight provides an update on the molecular mechanism of cognitive impairment due to REM sleep deprivation in the hippocampus. Finally, Chapter Nine presents the most frequently used evaluation tools and procedures of early neurorehabilitation in the acute hospital.

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Table of Contents

Preface

Chapter 1. Sequencing Human Genome to Study the Correlation between Genes and Violence
A. Hameed Khan, PhD
London, UK

Chapter 2. The Effect of CNS Drugs and Substances on Neurotransmission of REM Sleep
Kyriaki Astara¹, MD, Paschalis Steiropoulos², MD, PhD, MSci, Konstantinos I. Gourgoulianis¹, MD, PhD, and Nicholas-Tiberio Economou²’³ MD, PhD, MSci
¹Department of Respiratory Medicine, Faculty of Medicine, University of Thessaly, Larissa, Greece
²MSc Programme in Sleep Medicine, Medical School, Democritus University of Thrace, Alexandroupolis, Greece
³Sleep Study Unit, Department of Psychiatry, National and Kapodistrian University of Athens School of Medicine, Eginition Hospital, Athens, Greece

Chapter 3. Social Cognition: A Promising Therapeutic Target in Schizophrenia
Lejla Mustoo Başer, Pınar Ünal Aydın and Orkun Aydın
Department of Psychology, International University of Sarajevo, Sarajevo, Bosnia and Herzegovina

Chapter 4. Presentation of Selected Methods of Speech and Language Neurorehabilitation in Patients after Brain Injury Treatment
Maria Izabela Mielnik PhD
Clinic of Rehabilitation, University Clinical Center in Gdańsk, Poland; Department of Nursing Management, Medical University of Gdańsk, Poland

Chapter 5. In Vitro Toxicology Studies in Neuroblastoma Cells
Merve Bacanlı¹ and Hatice Gül Anlar²
¹University of Health Sciences Turkey, Gülhane Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Ankara, Turkey
²Zonguldak Bulent Ecevit University, Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Zonguldak, Turkey

Chapter 6. The Role of the Kynurenine Pathway in Huntington’s Disease-Linked Neuroinflammation
Graciela Cárdenas¹, PhD, Clara Leticia Miranda-Narvaez², BSc, José Pedro Elizalde-Díaz³, PhD, Eduardo Martínez-Martínez³, PhD; and Juan Carlos Martínez-Lazcano², PhD
¹Departamento de Neurología y Enfermedades Neuro-Infecciosas, Instituto Nacional de Neurología y Neurocirugía MVS CDMX, México
²Laboratorio de Neurofarmacología Molecular y Nanotecnología, Instituto Nacional de Neurología y Neurocirugía MVS CDMX, México
³Laboratorio de Comunicación Celular y Vesículas Extracelulares, Instituto Nacional de Medicina Genómica, CDMX, México

Chapter 7. Functional Balance Assessment in the Acute Neurorehabilitation after Cerebellopontine Angle Tumor Surgery
Natasa Kos¹, Marusa Brcar¹, Marko Brcar¹ and Tomaz Velnar²
¹Medical Rehabilitation Unit, University Medical Centre Ljubljana, Ljubljana, Slovenia
²Department of neurosurgery, University Medical Centre Ljubljana, Ljubljana, Slovenia

Chapter 8. The Molecular Mechanism of Cognitive Impairment Due to REM Sleep Deprivation in the Hippocampus: An Update
I. Long, PhD
Biomedical science programme, School of Health Sciences, Universiti Sains Malaysia, Kota Bharu, Kelantan, Malaysia

Chapter 9. Neurorehabilitation in the Acute Hospital
Natasa Kos¹ and Tomaz Velnar²
¹Medical Rehabilitation Unit, University Medical Centre Ljubljana, Ljubljana, Slovenia
²Department of Neurosurgery, University Medical Centre Ljubljana, Ljubljana, Slovenia

Index