Horizons in Cancer Research. Volume 83


Hiroto S. Watanabe

Series: Horizons in Cancer Research
BISAC: MED062000

This volume includes seven chapters that present some of the latest advancements in cancer research. Chapter One studies the correlation between smoking and cancer using the sequenced human genome. Chapter Two discusses glucose-regulated protein 78-mediated regulation of epithelial-mesenchymal transition, the apoptotic and autophagic signaling pathways, and how it can be used as a therapeutic against cancer. Chapter Three discusses new approaches in the treatment of hodgkin lymphoma. Chapter Four includes a review of the etiology, diagnosis and therapeutic management of rare pancreatic tumors. Chapter Five introduces recent progress on the mechanism of action and predictive biomarkers of mitomycin C using a genome-scale CRISPR/Cas9 knockout screening approach. Chapter Six discusses ultrasonography, endometrial sampling, magnetic resonance imaging, and computed tomography in the context of endometrial cancers. Finally, Chapter Seven discusses treatment options for papillary thyroid carcinoma.

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Table of Contents


Chapter 1. The Impact of Sequencing the Human Genome and its Correlation between Smoking and Cancers
A. Hameed Khan, PhD
Division of Genetics & Robotics NCMRR (National Center for Medical Rehabilitation Research) National Institutes of Health (NIH), Silver Spring, MD, USA

Chapter 2. Unraveling the GRP78 Paradox: From Cancer Promotion to Suppression
Adria Hasan1,2, Sana Parveen1,3, Suroor Fatima Rizvi1,2 and Snober S. Mir1,2,*
1Molecular Cell Biology Laboratory, Integral Information and Research Centre-4 (IIRC-4), Integral University, Lucknow, Uttar Pradesh, India
2Department of Bioengineering, Faculty of Engineering, Integral University, Lucknow, Uttar Pradesh, India
3Department of Biosciences, Faculty of Science, Integral University, Lucknow, Uttar Pradesh, India

Chapter 3. Novel Approaches in Hodgkin Lymphoma
S. Paydas, MD
Department of Oncology, Cukurova University, Adana, Turkey

Chapter 4. Rare Malignant Tumors of the Pancreas
M. Cantalejo Díaz1, X. Duque Álvarez2, A. Palomares Cano1, C. Alcázar López2, M. Serradilla Martín1,3 and J.M. Ramia Ángel2,4,5
1Department of Surgery, Hospital Universitario Miguel Servet, Zaragoza, Spain
2Department of Surgery, Hospital General Universitario, Alicante, Spain
3Instituto de Investigación Sanitaria Aragón, Zaragoza, Spain
4ISABIAL, Alicante, Spain
5Universidad Miguel Hernández, Elche, Spain

Chapter 5. Mitomycin C Selectively Eliminates BRCA2 Monoallelic and Biallelic Mutant Tumors
Fangfei Peng, Jiayan Shen and Jing-Yu Lang
The CAS_Key Laboratory of Tissue Microenvironment and Tumor, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China

Chapter 6. Diagnosis and Preoperative Evaluation in Endometrial Cancers
K. Uzel1, MD and I. Lakhno2, MD, PhD
1Department of Obstetrics and Gynecology, Erzincan Binali Yıldırım University Mengucek Gazi Training and Research Hospital, Erzincan, Turkey
2Department of Perinatology, Obstetrics and Gynecology, Kharkiv Medical Academy of Postgraduate Education, Kharkiv, Ukraine

Chapter 7. Recurrent Laryngeal Nerve Invasion
Sachender Pal Singh
HCG Cancer Hospital, Ranchi, India


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