Horizons in Cancer Research. Volume 81


Hiroto S. Watanabe (Editor)

Series: Horizons in Cancer Research

BISAC: MED062000

This edited volume presents seven chapters detailing recent progress in the field of cancer research. Chapter One explores the application of robotic surgery to radical cystectomy, highlighting patient selection, surgical approach, perioperative and oncologic outcomes as well as some areas of controversy in the literature. Chapter Two describes the principles of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy procedures with its potential risks for patients and staff. Chapter Three discusses findings related to ISG15 and protein ISGylation, and their association with interferon signaling in cancer. Chapter Four describes the potential for MCF-7 cells to curb or counteract breast cancer. Chapter Five discusses the potential of emerging technologies in breast conserving treatment. Chapter Six reviews the current literature surrounding the basis of employing the immune system for the treatment of the various non-melanoma skin cancers (NMSC), discusses approved immunotherapies for each type of NMSC as well as indications for use, and synthesizes ongoing investigational studies of immunomodulatory agents for these diseases. Finally, Chapter Seven discusses the use of gene therapy in management of squamous cell carcinoma.

Table of Contents


Chapter 1. Robotic Radical Cystectomy: A Review of Techniques, Outcomes, and Controversies
(Michael J. Whalen, Michael W. Helbig, Jacob Oppenheimer, George Khludenev and Melinda Fu – Department of Urology, George Washington University Hospital, Washington, DC, US, et al.)

Chapter 2. Cytoreductive Surgery and Hyperthermic Intra-peritoneal Chemotherapy: Procedures, Potential Risks and Outcomes
(Kim Govaerts and Brendan Moran – Hospital East-Limburg, Genk, Belgium, et al.)

Chapter 3. ISG15: An Interferon-Stimulated Gene with Critical Functional Implications in Cancer
(Josué Orlando Ramírez-Jarquín, Jesús Zepeda-Cervantes, Noé Santiago Alavez-Pérez and Angeles C. Tecalco-Cruz – Departamento de Neuropatología Molecular–Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico City, México, et al.)

Chapter 4. MCF 7 Cells – A Model towards Breakthrough in Breast Cancer Therapy
(Deena Priscilla H. and Jasmine R. – Department of Biotechnology, Bishop Heber College, Trichy, South India)

Chapter 5. Progress in Breast Conserving Treatment: Margin Assessment, Irradiation, Ablation
(Chen Yuan, Jie Zhang and Shouju Wang – Department of Radiology, Nanjing Medical University, Jiangsu, China)

Chapter 6. Immunotherapies in Non-Melanoma Skin Cancers
(Rohit Gupta, Riyad N.H. Seervai, Shangyi Fu and Hung Q. Doan – School of Medicine, Baylor College of Medicine, Houston, TX, US, et al.)

Chapter 7. Squamous Cell Carcinoma: Etiology and Advances in the Strategic Management
(Muhammad Imran Qadir – Institute of Molecular Biology and Biotechnology, Bahauddin Zakariya University, Multan, Pakistan)


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