Horizons in Cancer Research. Volume 75


Hiroto S. Watanabe (Editor)

Series: Horizons in Cancer Research
BISAC: MED062000

Horizons in Cancer Research. Volume 75 analyses the strategic actions taken by the UK in the fight against cancer, reviewing the key investments and funding made available in the country.

Following this, the authors discuss how efficient targeting of thioredoxin with compounds and proper knowledge of their mechanism of action may be an efficacious therapeutic intervention for cancer.

This compilation goes on to xplore the otologic complications secondary to radiotherapy for nasopharyngeal cancer cases to provide a clinical perspective on this issue.

An extensive review of the published studies about metastatic colorectal cancer kinetics and changes of growth curves under the pressure of pharmacological treatments is presented, and variables related to tumor cell kinetics derived from radiologic evaluations are discussed.

The authors propose a new post treatment cancer care involving the systemic administration of nanomolar concentrations of drag-reducing polymers that aims to avoid metastasis following cancer surgery.

A study is carried out to compare the molecular mechanism of cytochrome P450 enzyme family members on breast cancer, as well as to compare the distinct biological processes with each other.

This compilation closes with a guide for researchers concerning preserving the heterogeneity of breast cancer cell lines in terms of either isolation, selection or culture method models in order to understand the limitations of various methods.

Table of Contents

Table of Contents


Chapter 1. Advanced Technologies for Cancer Care in the UK: Current and Future Strategic Directions
(Barbara Camanzi, PhD, Science and Technology Facilities Council, UK Research and Innovation, Harwell Didcot, UK)

Chapter 2. The Molecular Mechanisms to Functional Significance of Selective Targeting of the Redox Active Thioredoxin System as an Effective Therapy Towards Cancer Elimination
(Nikhilesh Joardar, and Santi P. Sinha Babu, Parasitology Laboratory, Department of Zoology, Siksha-Bhavana, Visva-Bharati, Santiniketan, West Bengal, India, and others)

Chapter 3. The Otologic Complications of the Radiotherapy Treatment of Nasopharyngeal Cancer
(Ayca Ant, MD, and Omer Yazici, MD, Department of Otorhinolaryngology, Head and Neck Surgery, University of Health Sciences Ankara A.Y. Oncology Education and Research Hospital, Ankara, Turkey, and others)

Chapter 4. Growth Rate of Metastatic Colorectal Cancer: Evidence from Clinical Trials
(G. A. Colloca, A. Venturino and D. Guarneri, Oncologia Medica Imperiese, Imperia, Italy)

Chapter 5. Systemic Administration of Drag-Reducing Polymers to Combat Metastasis by Transforming Local Turbulence in Circulation into Laminar Blood Flow
(Alexander Pinkowski and Walter Lilienblum, Retired Scientist, Eauze, France, and others)

Chapter 6. Expressions of Cytochrome P450 Family and Molecular Mechanisms in Breast Cancer
(Serpil Oğuztüzün, Bilge Aydın Türk and Işıl Yıldırım, Department of Biology, Kırıkkale University, Kırıkkale, Turkey)

Chapter 7. Methods and Protocols for the Primary Isolation and In Vitro Culture of Breast Cancer Cells
(Cherie Ann Kruger, PhD, and Heidi Abrahamse, PhD, Laser Research Centre, Faculty of Health Sciences, University of Johannesburg, Johannesburg, South Africa)


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