Horizons in Cancer Research. Volume 74

Hiroto S. Watanabe (Editor)

Series: Horizons in Cancer Research
BISAC: MED062000

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Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick

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The opening chapter of this compilation extensively reviews scientific literature analyzing new molecular targets, ongoing research and future perspectives in the management of gastroenteropancreatic neuroendocrine neoplasms, a rare group of pathologically and clinically heterogeneous tumors.

The significance of PI3K pathway components in lung cancer progression are highlighted, as well as possible therapeutic targets that can be explored in an effort to control the disease.

Following this, the authors assess the contributions of flavin-containing monooxygenases 3 along with cytochrome P450 enzymes in Bu metabolic pathways, and analyze their effects on Bu kinetics.

The role of the pro-tumorigenic cytokines and the significance of dysregulated notch signaling in the progression of colonic inflammation and carcinogenic transformation is also discussed.

The current concepts of nutritional oncology in head and neck cancer patients are revised through a systematic literature search. Significant malnutrition has been reported due to several factors, such as a reduced dietary intake due to dysphagia and odynophagia, or catabolic factors secreted by the head and neck tumors.

Lastly, an overview of cervical cancer screening around the world is provided. In the United States, a combination of HPV-testing and cytology method, the HPV-test-alone, and cytology-alone are widely performed.
(Imprint: Nova Medicine and Health)

Preface

Chapter 1. Medical Treatment in Gastroenteropancreatic Neuroendocrine Neoplasms: A Look into the Future
(Mariangela Torniai, Laura Scortichini, Francesca Tronconi, Marta Dottori, Michela Burattini and Rossana Berardi, PhD, Clinica Oncologica, Università Politecnica delle Marche, AOU Ospedali Riuniti di Ancona, Italy)

Chapter 2. The PI3K Pathway Components and Their Role in Lung Cancer: Progression to Therapeutics
(Lakhon Kma, PhD, and Taranga Jyoti Baruah, Department of Biochemistry, North Eastern Hill University, Shillong, Meghalalya, India)

Chapter 3. Busulphan Metabolic Pathway and Possible Drug Interactions
(Ibrahim El-Serafi, MD, PhD and Moustapha Hassan, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden and Faculty of Medicine, Port-Said University, Egypt, and others)

Chapter 4. Aberrant Notch Signaling in Sessile Serrated Adenoma and Serrated Pathway of Colorectal Cancer
(Lei Wang, MD, PhD, Wei Xin, MD, PhD, and Lan Zhou, MD, PhD, Department of Pathology, Case Western Reserve University, Cleveland, Ohio, US)

Chapter 5. Nutritional Status in Head and Neck Cancer Patients
(Chiara Bianchini, Andrea Catalano, Virginia Corazzi, Silvia Moretto, Andrea Ciorba and Stefano Pelucchi, ENT and Audiology Department, University Hospital of Ferrara, Italy)

Chapter 6. A Review of Cervical Cancer Screening and Prevention
(Sayaka Ikeda, Yutaka Ueda, Asami Yagi, Yusuke Tanaka, Nobuyuki Susumu and Tadashi Kimura, Department of Gynecology, Mita Hospital, International University of Health and Welfare, Tokyo, Japan, and others)

Index

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