Horizons in Cancer Research. Volume 68


Hiroto S. Watanabe (Editor)

Series: Horizons in Cancer Research
BISAC: MED058160

High-grade gliomas are the most frequent primitive brain malignancies of the adult and account for approximately 60-75% of all gliomas. Chapter One concludes the progress in the management of high-grade gliomas requires the simultaneous and synergic effort of a multitude of health professionals including neurosurgeons, neuroncologists, neurointerventionalists, radiologists, immunologists and neuropathologists among others. Chapter Two describes the fundamental molecular mechanisms involved in the understanding of metastatic growth, the role of some metastasis suppressor proteins in the regulation of these processes in different types of cancer, and the clinical implications of these metastasis suppressors. Chapter Three highlights the reported knowledge regarding the secretion, regulation and therapeutic potential of melatonin in the prevention of cancer. Chapter Four reviews the current status of different oncolytic viruses and the molecular mechanism of viral oncolysis in the context of thoracic malignancies. Chapter Five suggests Coordination Dynamics Therapy can inhibit the growth of different kinds of cancer, especially breast cancer. Chapter six argues that the long term health outcomes of bilateral surgical oophorectomy justify that in the majority of cases, the defect of hormonal and metabolic equilibrium leads to decreased cellular estrogen surveillance and an increase in both morbidity and mortality. Chapter seven evaluates the importance of assessing HPV status as a clinically relevant biomarker and to study the therapeutic implications for the appropriate management of HPV-related OPSCC. Chapter eight covers the complex and multiform network of actions by MicroRNA, and the value of miRNAs in oncology as diagnostic and prognostic indicators. (Imprint: Nova Biomedical)

Table of Contents

Table of Contents


Chapter 1. Multimodal Treatment of High Grade Glioma
Federico Caporlingua, MD, Alessandro Caporlingua, MD, Alessandra Marongiu, MD, Maria Pia Tropeano, MD and Maurizio Salvati (Department of Neurology and Psychiatry, Neurosurgery, “Sapienza” University of Rome, Rome, Italy, and others)

Chapter 2. Metastasis Suppressor Genes: Function and Regulation
Patricio Barros-Núñez, Mónica Alejandra Rosales-Reynoso and Sofía Dumois-Petersen (Center for Biomedical Research of the West, IMSS, Guadalajara, México)

Chapter 3. Pineal Gland Secretion: The Regulation and Therapeutic Role in Cancer
Munibah Qureshi, Armughan Haider and Adeeb Shehzad (Department of biomedical Engineering and Sciences, School of Mechanical and Manufacturing Engineering, National University of Sciences and Technology, Islamabad, Pakistan)

Chapter 4. Oncolytic Virotherapies in Thoracic Cancers
Zeeshan Ahmad and Robert A. Kratzke (Department of Medicine, Division of Hematology, Oncology, and Transplantation, University of Minnesota Medical School, Minneapolis, USA)

Chapter 5. Breast Cancer Growth Inhibition via Coordination Dynamics Therapy]
Giselher Schalow (Private Researcher)

Chapter 6. Oophorectomy in Premenopausal Women Is Neither a Preventive nor Curative Measure against Breast Cancer
Zsuzsanna Suba (National Institute of Oncology, Surgical and Molecular Tumor Pathology Center, Budapest, Hungary)

Chapter 7. Human Papilloma Virus-Related Oropharyngeal Cancer: An Update
Sana Ennouri, Moncef Sellami, Ines Ayadi, Nabil Toumi, Afef Khanfir, Boutheina Hammami, Ilhem Charfeddine, Malek Mnejja, Mounir Frikha and Abdelmonem Ghorbel (Department of Otorhinolaryngology-Head and Neck Surgery, Habib Bourguiba University Hospital, Sfax, Tunisia, and others)

Chapter 8. MicroRNAs in Thyroid Carcinomas: A Work in Progress
Luca Roncati, Antonio Manenti, Giuseppe Barbolini and Antonio Maiorana (Departments of Pathology and Surgery, University of Modena and Reggio Emilia, Modena, Italy)


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