Horizons in Cancer Research. Volume 62


Hiroto S. Watanabe (Editor)

Series: Horizons in Cancer Research
BISAC: SCI026000

This book presents original results on the leading edge of cancer research. Chapter One summarizes what is currently known regarding the epigenetic regulation of osteosarcoma pathways and oncogenes, as well as clinical trials of drugs that exert epigenetic regulation. Chapter Two critically discusses the role of ECM-dependent signaling in osteosarcoma progression. Chapter Three illustrates the harmful effects of ultraviolet radiation exposure by focusing on photocarcinogenesis. Chapter Four examines the psychology of sunscreen use and outlines the key psychological factors associated with sunscreen use. Chapter Five reviews the cellular and molecular mechanism of Regulatory T cells (Tregs) and Transforming Growth Factor-â mediating cervical cancer development. Chapter Six examines the affect of the American cranberry extract on expression of insulin-like growth factor-I and insulin-like growth factor binding proteins in human prostate cancer cells in vitro. Chapter Seven discusses the design of synthetic peptides to specifically interfere the papillomavirus binding factor/14-3-3beta binding to restore papillomavirus binding factor apoptotic functions. Chapter Eight examines brain development using correlations between Diffusion Kurtosis and neurite orientation dispersion and density imaging (NODDI) in neonates and young children. Chapter Nine highlights the opportunities that are available to prevent the late effects related to stress and fears, emphasizing the importance of teaching patients resiliency and how to cope. (Imprint: Nova Biomedical)

Table of Contents

Table of Contents


Chapter 1. Epigenetic Regulation in Osteosarcoma
Vi Nguyen, Carolyn Meyers, Alan Nguyen, Michelle A. Scott, and Aaron W. James (Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, USA, and others)

Chapter 2. Osteosarcoma Cell Functions: Focus on Extracellular Matrix Signaling
Nikitovic Dragana, Kavasi Rafaela-Maria, Moraiti Renata, Berdiaki Aikaterini, Aggelidakis John and George N. Tzanakakis (Department of Anatomy-Histology-Embryology, School of Medicine, University of Crete, Heraklion, Greece)

Chapter 3. The Long-Term Effects of Ultraviolet Radiation: Photocarcinogenesis
Jeffrey F. Scott, Elma Baron, and Meg R. Gerstenblith (Department of Dermatology, University Hospitals Case Medical Center and Case Western Reserve University, Cleveland, OH, USA)

Chapter 4. Skin Cancer and Sunscreen Use: Psychological Factors
David Hevey and Joana Cruz (Research Centre for Psychological Health, School of Psychology, Trinity College Dublin, Dublin, Ireland)

Chapter 5. Involvement of Treg Cells and TGFB in HPV Infection and Cervical Cancer Development
Julie Massayo Maeda Oda, Maria Angelica Ehara Watanabe and Karen Brajão de Oliveira (Federal University of Mato Grosso do Sul, UFMS, Campus Três Lagoas, Mato Grosso do Sul, MS, Brazil, and others)

Chapter 6. American Cranberry (Vaccinium macrocarpon) Extract Affects Expression of Insulin-Like Growth Factor-I and Insulin-Like Growth Factor Binding Proteins in Human Prostate Cancer Cells in vitro
Brendan T. McKeown, Joseph Kim, Kunal Patel, Catherine C. Neto and Robert A. R. Hurta (University of Prince Edward Island, Charlottetown, PE, Canada, and others)

Chapter 7. Design of Synthetic Peptides to Specifically Interfere the PBF/14-3-3b Binding to Restore PBF Apoptotic Functions
Paola Castillo-Juárez, Zaira E. Arellano-Anaya, Rogelio López-Martínez, Eva Elda Soriano-Pérez, and Blanca L Barrón (Department of Microbiology, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Carpio y Plan de Ayala S/N, Casco de Santo Tomás, México)

Chapter 8. Study of Brain Development using Correlation between Diffusion Kurtosis and NODDI Metrics in Neonates and Young Children
Shaheen Ahmed, Zhiyue J. Wang and Nancy K. Rollins (Department of Radiology, Children’s Medical Center, Dallas, TX, USA, and others)

Chapter 9. After the Cure: Empowering Survivors through Resilience, Knowledge, Hopes and Dreams
Luisa M. Massimo (Department of Pediatric Hematology and Oncology, G. Gaslini Scientific Children’s Hospital, Genoa, Italy)


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