Heparin: Structure, Drug Delivery Applications and Clinical Outcomes


Nicole B. Wilkinson (Editor)

Series: Pharmacology – Research, Safety Testing and Regulation
BISAC: MED058170

Heparin is a highly sulphated glycosaminoglycan discovered about 90 years ago, and since then is widely used in medicine as an anticoagulant drug. Antithrombin (AT) is a small protein molecule that inactivates several enzymes of the coagulation system. This book discusses the clinical applications of heparin; new antithrombotic and anti-platelet drugs that can be used instead of heparin; and heparin’s effect on vascular health. (Imprint: Nova Biomedical )

Table of Contents

Table of Contents


Chapter 1. Heparin: Which Molecule? What Clinical Applications?
Egidio Imbalzano, Michele Creazzo, Giovanni Trapani, Antonio Stellitano, Marta Zucco, Sebastiano Quartuccio, Giuseppina Lizio, Giuseppe Dattilo and Antonino Saitta (Department of Internal Medicine, University of Messina, Italy, and others)

Chapter 2. Moving Away from Heparin: The New Antithrombotic And Anti-Platelet Drugs
Leanne F. Harris and Anthony J. Killard (Biomedical Diagnostics Institute, National Centre for Sensor Research, Dublin City University, Dublin, Ireland, and others)

Chapter 3. Heparin and Vascular Health
Linda Hiebert, and Jimin Liu (Department of Veterinary Biomedical Sciences, University of Saskatchewan, Saskatoon, Canada, and others)

Chapter 4. Intracellular Transport of Heparin-Binding EGFLike Growth Factor (HB-EGF) and the Possibility of Targeted Drug Delivery to Distinct Intracellular Compartments
Miki Hieda (Graduate School of Medicine and Health Science, Osaka University, Osaka, Japan)


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