Helicobacter pylori: From Diagnosis to Treatment

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Alexandra Curr (Editor)

Series: Digestive Diseases – Research and Clinical Developments
BISAC: MED022090, MED031000

Helicobacter pylori is classified as a gram-negative, spiral and microaerophilic bacterium and considered one of the most common causes of gastric infections worldwide. It was isolated from gastric biopsy specimens from patients with chronic gastritis and peptic ulcers in 1983.

Non-pylori Helicobacter species may occasionally colonize the human stomach causing gastritis, but the prevalence is unknown. As such, in this compilation antral biopsies from 484 patients were examined for H. pylori by culture and quantitative polymerase chain reaction. In addition, the biopsies were examined for Helicobacter spp. by polymerase chain reaction.

The authors summarize and compare the historical and novel methods used for the diagnosis and treatment of H. pylori infection.

This collection goes on to assess how knowledge about the characteristics, advantages, and limitations of various diagnostic methods for H. pylori allows for the choice of the appropriate technique in the clinical practice or research setting.

Lastly, the authors propose that every child with suspected H. pylori infection should be carefully evaluated by a pediatric gastroenterologist before deciding whether to perform upper gastrointestinal endoscopy and any eradication therapy. (Imprint: Nova Medicine and Health)

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Table of Contents

Preface

Chapter 1. General Characteristics, Main Virulence Markers and New Approaches in the Control of Helicobacter pylori
(Bruna Almeida Furquim de Camargo, Larissa Spósito, Maurício Palmeira Chaves De Souza, Matheus Aparecido dos Santos Ramos, Giovanna Capaldi Fortunato, Marlus Chorilli and Taís Maria Bauab, Department of Biological Sciences, São Paulo State University, School of Pharmaceutical Sciences, Araraquara, SP, Brazil, and others)

Chapter 2. Diagnostic of Helicobacter Species and Resistance to Antibiotics
(Leif Percival Andersen, Melodi Yusibova, Agnes Tving Stauning, Michael Patrick Achiam, Andreas Munk Petersen, Malene Roed Spiegelhauer, Amalie Bøge Rud Hansen, Inger Bak Andersen, Henrik Hasman and Stine Sloth, Department of Clinical Microbiology, Rigshospitalet, Copenhagen, Denmark, and others)

Chapter 3. Current Approaches for the Diagnosis and Treatment of Helicobacter pylori
(P. Ashwini, P. Sushma, Anisha S. Jain, M. N. Nagendra Prasad, Kollur Shiva Prasad, S. Chandrashekar, D. Chandan and S. Chandan, Division of Microbiology and Tissue Culture, School of Life Sciences, JSS Academy of Higher Education and Research, Mysuru, Karnataka, India, and others)

Chapter 4. An Overview on Helicobacter pylori Clinical Management
(Mariana Miranda Sampaio, Maria Luísa Cordeiro Santos, Breno Bittencourt de Brito, Filipe Antônio França da Silva, Hanna Santos Marques, Vinícius Lima de Souza Gonçalves, Natália Oliveira e Silva and Fabrício Freire de Melo, Instituto Multidisciplinar em Saúde, Universidade Federal da Bahia, Vitória da Conquista, Bahia, Brazil, and others)

Chapter 5. The Current Management of Helicobacter pylori Infection in Children
(Marco Manfredi, Pierpacifico Gismondi, Bernardino Ferrari, Silvia Iuliano and Giancarlo Gargano, Pediatric Unit, Sant’Anna Hospital, Maternal and Child Department, Azienda USL-IRCCS di Reggio Emilia, Italy, and others)

Index

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