Handbook of Macrophages: Life Cycle, Functions and Diseases (CD included)


Rikiya Takahashi (Editor)
Hibiki Kai (Editor)

Series: Cell Biology Research Progress, Immunology and Immune System Disorders
BISAC: SCI008000

Macrophages are widely distributed innate immune cells, which play a pivotal role not only in the primary response to pathogens but also in adaptive immune response, in tissue repair and in the maintenance of local tissue homeostasis. This book includes current research in the life cycle, functions and diseases associated with macrophages. Topics discussed include macrophages as regulatory and effector cells in the immune system; macrophages from human pluripotent stem cells; mucosal macrophage phenotype and functionality in homeostasis and pathology; macrophage plasticity and polarization; defective macrophage function in Crohn’s disease; macrophages in viral infection and atherosclerosis; and macrophage polarization in the course and treatment of autoimmune diseases. (Imprint: Nova Biomedical )


Table of Contents

Table of Contents


Macrophages and Tuberculosis
(Clíona Ní Cheallaigh, Celia Peral de Castro, Michelle M. Coleman, Jayne C. Hope, James Harris, School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Pearse Street, Dublin, Ireland, and others)

Nitric Oxide: “The Double-Edged Sword” of Macrophages in the Immune Defense
(András Hrabák, Department of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, Budapest, Hungary)

Macrophages from Human Pluripotent Stem Cells
(Sally A. Cowley, Karl R. Karlsson, Bonnie van Wilgenburg, Gemma Carter, Cathy Browne, Jane Vowles, Fernando Martinez Estrada, Annegret Pelchen-Matthews, Joanna Miller, Michael D. Moore, William James, Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, United Kingdom, and others)
Free Download Available 

Mucosal Macrophages: Phenotype and Functionality in Homeostasis and Pathology
(Andrew Foey, School of Biomedical and Biological Sciences, University of Plymouth, Drake Circus, Plymouth, United Kingdom)

Macrophage Plasticity and Polarization: Cell Signaling Mechanisms and Roles in Immunity
(Rafael Paletta-Silva, José Roberto Meyer-Fernandes, Instituto de Bioquímica Médica, Universidade Federal do Rio de Janeiro, UFRJ, Rio de Jameiro, Brazil)
Free Download Available 

Mechanisms of Macrophage-Dependent Regulation of Hepatocyte Functions
(L.E. Panin, I.F. Usynin, Scientific Research Institute of Biochemistry, Siberian Branch of the Russian Academy of Medical Sciences, Novosibirsk, Russia)

HIV-1 Tat Protein Induces TNF-a and IL-10 in Human Monocyte/Macrophage Cells
(Planès Rémi, Mzoughi Olfa, Ben Haij Nawal, Leghmari Kaoutar, Contreras Xavier, Bahraoui Elmostafa, Infections Virales: Persistance, Réponse de L’Hôte et Physiopathologie Unité, Toulouse Cedex, France, and others)

Diverse Functionality of Macrophages after Axonal Injury to the Central Nervous System
(Ernesto A. Salegio, Department of Neurosurgery, University of California-San Francisco, Tracy, California, USA)

Macrophage Stimulation and β-D-Glucans as Biological Response Modifiers: The Role in Experimental Tumor Development
(T.A. Korolenko, Y.A. Kisarova, E.E. Filjushina, M.A. Dergunova, E. Machova, Institute of Physiology SB RAMS, Novosibirsk, Russia, and others)

Hepatic Macrophages and Macrophages with Different Functions in Hepaticfibrosis
(Hossain Md. Golbar, Jyoji Yamate, Veterinary Pathology, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Izumisano City, Osaka, Japan)
Free Download Available

Macrophage in Inflammation and Healing: Relationship with Biomaterials
(Maria A. Souza, Camilla C. G. Moura, Instituto de Ciências Biomédicas, Faculdade de Odontologia, Universidade Federal de Uberlândia, Uberlândia, MG, Brazil)

Macrophage Polarization in the Course and Treatment of Autoimmune Disease
(Jian Hong, Zhengyi Wang, Lei Shen, Jingwu Z. Zang, Department of Neuroimmunology, GlaxoSmithKline Research and Development Center, Shanghai, China, and others)

The Functional Diversity of Kupffer Cells
(Masanori Nakamura, Hirotada Otsuka, Hideki Yagi, Yasuo Endo, Department of Oral Anatomy and Developmental Biology, School of Dentistry, Showa University, Hatanodai, Shinagawa-ku, Tokyo, Japan, and others)
Free Download Available 

Defective Macrophage Function in Crohn’s Disease
(A. Sarmento, N. Campos, R. Appelberg, F. Magro, CEBIMED, Biomedicine Research Center, Health Sciences Faculty, University Fernando Pessoa, Porto, Portugal, and others)

Macrophages in Viral Infection
(Yuko Nakamura-López, Laboratory of Molecular Biology, Consejo Estatal para la Prevencion del SIDA-Centro Ambulatorio para la Prevencion y Atencion del SIDA e Infecciones de Transmisión Sexual (COESIDA-CAPASITS Oaxaca), San Bartolo Coyotepec, Oaxaca, Mexico)

Macrophage and Atherosclerosis
(Yuchang Fu, University of Alabama at Birmingham, Alabama, USA)

Arginine Transport in Human Monocytes/Macrophages
(Amelia Barilli, Bianca Maria Rotoli, Rossana Visigalli, Ovidio Bussolati, Gian C. Gazzola, Valeria Dall’Asta, Department of Experimental Medicine, Section of General and Clinical Pathology, University of Parma, Parma, Italy)

Multiple Mechanisms Underlying Silent Cleanup of Apoptotic Cells
(Y. Kobayashi, Division of Molecular Medicine, Department of Biomolecular Science, Faculty of Science, Toho University, Funabashi, Japan)

The Roles of CD68 Expressing Macrophage Lineage Cells in Engineered Dental Pulp Tissues
(Tomoatsu Kaneko, Yusuke Yamanaka, Takashi Okiji, Division of Cariology, Operative Dentistry and Endodontics, Department of Oral Health Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan)

Macrophages: Life Cycle, Functions and Participation in the Pathogenesis of Atherosclerosis
(Kuniaki Hirose, Takashi Kiyanagi, Kazunori Shimada, Hiroyuki Daida,
Kazuhisa Iwabuchi, Department of Cardiovascular Medicine, Juntendo University School of Medicine, Institute for Environmental and Gender Specific Medicine, Tomioka, Urayasu City, Chiba, Japan, and others)
Free Download Available



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