Handbook of Genitourinary Medicine: New Research


Rashmi R. Singh (Editor)
Clinical Internship with Kriger Research Group International, Vancouver, British Columbia,

Series: Renal, Metabolic and Urologic Disorders
BISAC: MED088000

This book presents review articles in the study of genitourinary medicine. Topics include basic research that investigates the epigenetic mechanisms in urogenital cancers; the role of matrix metalloproteinases in urothelial cancers; the role of toll-like receptor genes in prostate cancers; recent emerging and novel treatment modalities in advanced metastatic renal cell and bladder carcinomas; novel mouse models for studying malformations in the genitourinary tract; the role of tissue engineering in genitourinary regenerative medicine; and clinical management of patients with Vesicoureteric reflux.

Apart from the very well-known Wilms tumor (a form of pediatric hereditary kidney tumors), little is known about pediatric nephritic syndrome and their genetic causes and clinical manifestations. Hence, a special chapter has been included that describes the recent genetic technologies that identify gene mutations in patients with pediatric nephritic syndrome. The specific gene mutations found in these patients are often associated with rapid renal failures, disease progression and poor survival outcome. Each of the articles presented by authors from all over the world are renowned and experts in their own field of research. The authors are based either in research and/or a clinical setting and the articles are only a summary of the view points of each of these authors. (Imprint: Nova Biomedical )

Table of Contents

Table of Contents

Preface pp. i-vii

Chapter 1. Emerging Trends in the Treatment of Kidney Cancers
(Rashmi R. Singh and Ravibhushan Singh, Scientific and Clinical Consultant, SciReg Pharma, Vancouver, BC, Canada)pp. 1-12

Chapter 2. Matrix Metalloproteinases: Role In Urothelial Cancer
(Rama Devi Mittal and Priyanka Srivastava, Department of Urology and Renal Transplantation, Sanjay Gandhi Pos Graduate Institute of Medical Science, Uttar Pradesh, India)pp. 13-32

Chapter 3. Toll-Like Receptor Genes and Prostate Cancer Risk
(Rama Devi Mittal and Raju Kumar Mandal, Department of Urology and Renal Transplantation, Sanjay Gandhi Post Graduate Institute of Medical Science, Uttar Pradesh, India) pp. 33-44

Chapter 4. Vesicourteric Reflux
(Andrew Moon, Nikhil Vasdev and Andrew C. Thorpe, Department of Urology, Freeman Hospital, Newcastle upon Tyne, UK)pp. 45-54

Chapter 5. Genetic Models for Genitourinary Malformations
(Irina B. Grishina, Department of Urology, New York University School of Medicine, New York, NY, USA)pp. 55-68

Chapter 6. From Bench to Patients: Advances in Genitourinary Regenerative Medicine
(S. Bouhout, A. Rousseau, F. Bouchard, A. Morissette, S. Chabaud
and S. Bolduc, Laval University, Quebec City, Quebec, Canada)pp. 69-96

Chapter 7. Chemotherapy in Invasive Bladder Cancer
(Nabil Ismaili, Medical Oncology, University Hospital Mohamed VI, Marrakech, Morocco)pp. 97-118

Chapter 8. The Genetics of Pediatric Nephrotic Syndrome
(Aiysha Abid, Centre for Human Genetics and Molecular Medicine, Sindh Institute of Urology and Transplantation, Karachi, Pakistan)pp. 119-142

Chapter 9. Epigenetic Modifications in Urooncology
(Muzeyyen Izmirli, Davut Alptekin and Ulkan Kilic, Bezmialem Vakif University, Medical School, Department of Medical Biology, Istanbul, Turkey, and others)pp. 143-168

Index pp. 169-181

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