Table of Contents
Table of Contents
Preface
Chapter 1. Glycosylphosphatidylinositol-anchored Proteins at the Boundary of Cell and Environment, Interior and Exterior Worlds – A “Historical” Introduction
Chapter 2. Biogenesis and Cell Surface Expression of GPI-AP
Chapter 3. Intrinsic Biophysical, Biochemical and Physiological Features of GPI-AP
Chapter 4. Release of GPI-AP
Chapter 5. Implications from the Structure, Function and Membrane Release of GPI-AP for Potential Clinical and Pharmaceutical Applications
Chapter 6. Conclusion
References
Index
Additional Information
Keywords: acetylcholinesterase, alkaline phosphatase, carcinoembryonic antigen, decay accelerating factor, endoplasmic reticulum, endoplasmic reticulum-associated destruction, endoplasmic reticulum-exit sites, exosomes, extracellular matrix, G protein-coupled receptor, glycosylphosphatidylinositol-anchored protein, GPI-anchored HDL-binding protein-1, GPI-specific phospholipase C/D, lipoprotein-like particles, milk fat globules, microvesicles, non-alcoholic fatty liver disease, non-alcoholic steatohepatitis, nodal vesicular particle, paroxysmale nocturnal hemoglobinuria, surfactant-like particles, T2D, type 2 diabetes, trans-Golgi network, Tamm-Horsfall glycoprotein, urokinase plasminogen activator receptor, variant surface glycoprotein
The manuscript will be of interest for basic and clinical researchers (biochemists, molecular biologists, geneticists, biotechnologists) engaged in the areas of membrane proteins, in general, and biomarkers, secretory proteins, serum proteins, in particular.