Glucose Uptake: Regulation, Signaling Pathways and Health Implications


Carter C. Johnson (Editor)
Davis B. Williams (Editor)

Series: Endocrinology Research and Clinical Developments
BISAC: MED027000

Insulin stimulates the uptake of glucose in several target tissues, including skeletal muscle and adipose tissue, thereby contributing to the decline in the blood glucose level. In this book, the authors present current research in the study of the regulation, signaling pathways and health implications of glucose uptake.

Topics include glucose uptake and transport regulation; the mechanisms that contribute to glucose homeostasis; expression and regulation of neuronal glucose transporters in health and disease; role for the microvasculature in glucose uptake in skeletal muscle; implications of diabetes on sperm glucose uptake and metabolism; the beneficial role of estrogen signaling in glucose homeostasis and energy expenditure; glucose uptake and androgen responsiveness of prostate cancer cells; regulation of intestinal glucose uptake by leptin; and the Ras superfamily of small GTP-binding proteins in glucose transporter type 4-mediated glucose uptake in insulin-responsive tissues. (Imprint: Nova Biomedical )

Table of Contents

Table of Contents


Glucose Uptake and Transport Regulation
(Evangelos Zoidis, Department of Nutritional Physiology and Feeding, Faculty of Animal Science and Aquaculture, Agricultural University of Athens, Athens, Greece)

Glucose Uptake: Knowledge from In Vivo, In Situ and In Vitro Studies and Health Implications
(Fatima Regina Mena Barreto Silva, Maris Jadna Silva Frederico, Allisson Jhonatan Gomes Castro, Gabrielle Da Luz, Delsi Altenhofen, Luisa Helena Cazarolli, Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Universitário, Bairro Trindade, Florianópolis, SC, Brazil, and others)

Expression and Regulation of Neuronal Glucose Transporters in Health and Disease
(Aníbal I. Acuña, Angara Zambrano, Ilona I. Concha, Maite A. Castro, Instituto de Bioquímica y Microbiología, Facultad de Ciencias, Universidad Austral de Chile, Valdivia, Chile)
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Role for the Microvasculature in Glucose Uptake in Skeletal Muscle
(Dino Premilovac, Huei L.H. Ng, Stephen M. Richards, Eloise A. Bradley, Renee M. Dwyer, Stephen Rattigan, Michelle A. Keske, Menzies Research Institute Tasmania, and School of Medicine, University of Tasmania, Hobart, Australia)

Implications of Diabetes on Sperm Glucose Uptake and Metabolism
(T.R. Dias, M.G. Alves, A. Neuhaus-Oliveira, S. Socorro, B.M. Silva, P.F. Oliveira, CICS – UBI – Health Sciences Research Centre, University of Beira Interior, Covilhã, Portugal)

Beneficial Role of Estrogen Signaling in Glucose Homeostasis and Energy Expenditure
(Zsuzsanna Suba, National Institute of Oncology, Budapest, Hungary)

Glucose Uptake and Androgen Responsiveness of Prostate Cancer Cells
(C.V. Vaz, M.G. Alves, R. Marques, P.F. Oliveira, C.J. Maia, S. Socorro, CICS-UBI – Health Sciences Research Center, University of Beira Interior, Covilhã, Portugal)

Regulation of Intestinal Glucose Uptake by Leptin
(Jaione Barrenetxe, Carmen Fanjul, Robert Ducroc, Maria Pilar Lostao, Department of Nutrition, Food Science and Physiology, University of Navarra, Pamplona, Spain, and others)

The Ras Superfamily of Small GTP-Binding Proteins in Glucose Transporter Type 4-Mediated Glucose Uptake in Insulin-Responsive Tissues
(Takaya Satoh, Laboratory of Cell Biology, Department of Biological Science, Graduate School of Science, Osaka Prefecture University, Gakuen-cho, Naka-ku, Sakai, Osaka, Japan)


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