Gastrointestinal Cancers: Prevention, Detection and Treatment. Volume 2


Amit Kumar Tyagi and Sahdeo Prasad (Editors)
Department of Experimental Therapeutics, The University of Texas MD Anderson Center, Houston, TX, USA

Series: Cancer Etiology, Diagnosis and Treatments
BISAC: MED062000

Gastrointestinal cancer is the most frequently diagnosed type of cancer all around the globe. Gastrointestinal cancer is the cancer of different organs of the digestive system including the esophagus, stomach, liver, gallbladder, pancreas, small intestine, large intestine, rectum and anus. The common cause of gastrointestinal cancer may be microbial infection, smoking, alcohol consumption, high fat food, age, race, genetic pattern and geographical location. Gastrointestinal cancer accounts more than 20 percent of all newly diagnosed cancer cases in United States, where gastric cancer is the fourth-most-common type of cancer and the second-highest cause of cancer deaths. Pancreatic cancer is also a very lethal cancer and its symptoms appear when the cancer is in advanced stage. Other gastrointestinal cancers including Liver (hepatic), gallbladder, and colorectal cancer have received considerable attention due to the rising incidence in last few decades. Some other gastrointestinal cancers are not very common and usually associated with cancer of respective organs such as esophageal cancer, cholangiocarcinoma or bile duct cancer, carcinoid tumor, pancreatic islet cell cancer, and duodenal cancer. This book provides a summary of various gastrointestinal cancer history, present and future. In this book, numerous international experts of gastrointestinal cancer have involved, where authors have provided a complete view of the most common and widely used diagnostic methods, and also explaining the unusual techniques and the most innovative complementary methods not yet used in clinical practice. Contributors have also described the latest findings and the various clinical manifestations related to gastrointestinal cancer prevention and treatment. It covers numerous discoveries and inventions in the field of gastrointestinal cancer detection, and analysis. (Imprint: Nova Biomedical)

Table of Contents

Table of Contents


Chapter 1. Colorectal Polyps and Carcinoma: Role of the Pathologist
Nilesh D. Kashikar and Monica T. Garcia-Buitrago (Department of Pathology and Laboratory Medicine, Miller School of Medicine, University of Miami, FL, USA)

Chapter 2. Exocrine Pancreatic Cancer
Pastorelli Davide, Soldà Caterina and Ziampiri Stamatia (Rare Tumors Unit, Veneto Institute of Oncology– IRCCS, Padova, Italy)

Chapter 3. Ancillary Diagnostic Opportunities: Harnessing Circulating Tumor Cells, Tumor Educated Platelets, and Extracellular Vesicles for the Early Detection of Pancreatic Cancer
Eric Cruz and Surinder K. Batra (Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE USA, and others)

Chapter 4. Borderline Pancreatic Adenocarcinoma: New Challenges in Management and Therapeutic Strategies
D. Pietrasz, M. Wagner, F. Huguet, and J.B. Bachet (Department of Digestive and Hepatobiliary Surgery, Pitié-Salpêtrière Hospital, APHP, Sorbonne University, UPMC University, Paris, France, and others)

Chapter 5. Pancreatic Cancer: Prevention, Detection and Treatment
Amir Avan, Mina Maftouh, Majid Ghayour-Mobarhan, Godefridus J. Peters, and Elisa Giovannetti (Molecular Medicine group, Department of Modern Sciences and Technologies, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran, and others)

Chapter 6. Past, Present and Future Perspectives on the Role of Systemic Chemotherapy for Management of Advanced Pancreatic Adenocarcinoma
Ahmed Abu-Zaid, Syed Osama Ahmad, Fouad Yousuf, Ahmed S Bux, Rasha Al-Shawaf, Fareeha K Abdulwali, Judie N Hoilat, Sana S Kadan, Saara A Mansoor, Mai Alshammari, Mohammed Abuzaid, Ayman Azzam, Wael Al-Kattan (College of Medicine, Alfaisal University, Riyadh, Saudi Arabia, and others)

Chapter 7. Current treatment paradigms in the management of Pancreatic Adenocarcinoma
Rupen Shah, Steven N. Hochwald and Moshim Kukar (Department of Surgical Oncology, Roswell Park Cancer Institute, Buffalo, NY, USA)

Chapter 8. Pancreatic Cancer: Art of Management. Past, Present, and Future
Elena Tsvetkova (Juravinski Hospital and Cancer Centre, Hamilton Health Sciences, Hamilton, Ontario, Canada)

Chapter 9. Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Mucinous Tumors of the Gastrointestinal Tract
Amanda K Arrington and Joseph Kim (Assistant Professor, Department of Surgery, Marshall University, Huntington, WV, USA, and others)

Chapter 10. Surgical Treatment of Biliary Tumors
Giorgio Ercolani, Alessandro Cucchetti, Matteo Cescon, Matteo Ravaioli, Massimo Del Gaudio, Chiara Zanfi, Giovanni Brandi, and Antonio D Pinna (Department of Medecine and Surgical Sciences, University of Bologna, Hospital Sant’Orsola-Malpighi, Bologna, Italy)

Chapter 11. Prevention, Diagnosis and Treatment of Hepatocellular Carcinoma
Sarah El-Nakeep and Omar Abdel-Rahman (Internal medicine department; Hepatology and gastroenterology Unit, faculty of medicine, Ain shams university, Cairo, Egypt, and others)

Chapter 12. The Application of Nanotechnology to Gastrointestinal Cancers
Veronica M. Ringel and Irving C. Allen (Graduate Program in Translational Biology, Medicine, and Health, Virginia Tech, Blacksburg, VA, USA, and others)

Chapter 13. Application of Quantitative Proteomics to Biomarker Discovery and Precision Medicine in Gastrointestinal Cancer
Chun-Hao Huang, Pei-Jing Pai and Shyh-Horng Chiou (Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan, and others)

Chapter 14. Systemic Inflammation Causing Multiple Clinical Symptoms in Gastrointestinal Cancer
Masahiko Shibata, Kenji Gonda and Seiichi Takenoshita (Saitama Medical University International Medical Center and Fukushima Medical University, Japan)

Chapter 15. Immunotherapies for Gastrointestinal Tumors: The State of the Art and Future Perspectives
Nise H. Yamaguchi (Immunology and medical oncology, Hospital Israelita Albert Einstein and Faculdade de Medicina da Universidade de São Paulo, Clinical Director of Instituto Avanços em Medicina, S. Paulo, SP, Brazil, and others)

Chapter 16. Gastrointestinal Cancers and Microbiome: Influence of Environmental Factors on Preventative and/or Therapeutic Modalities
Shahid Umar (Department of Surgery, University of Kansas Medical Center, Kansas City, KS, USA)


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