Frontiers in Leukemia Pharmacotherapy

Lunawati L. Bennett (Editor)
Professor of Pharmaceutical Sciences, Tenured Union University College of Pharmacy, Jackson, TN, US

Series: Cancer Etiology, Diagnosis and Treatments
BISAC: MED071000

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$230.00

Volume 10

Issue 1

Volume 2

Volume 3

Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick

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Frontiers in Leukemia Pharmacotherapy provides a comprehensive overview of the various leukemic disorders found in both children and adults, with an emphasis on current and novel treatment approaches for the healthcare practitioner. By focusing on the unique therapeutic challenges of leukemia, this book aims to meet the diverse needs of physicians, pharmacists, nurses, and other healthcare professionals with an interest in serving patients with leukemia.

This comprehensive book is divided into nineteen chapters. Content includes information on specific leukemic disease states in both children and adults. Written by researchers and clinical practitioners, chapters cover a wide array of leukemic topics. Topics include understanding the molecular and genetic basis of acute and chronic leukemia, pharmacology of anti-leukemic agents including traditional chemotherapies, targeted immunotherapy, and tyrosine kinase inhibitors. The epidemiology, etiology, pathogenesis, disease classification, clinical presentation, pathologic features, diagnosis, prognosis, and treatment guidelines for myelodysplastic syndrome, promyelocytic leukemia, pediatric and adult acute and chronic leukemia are other topics covered in more detail. Other topics include: Redox homeostasis occurring in leukemia and the role of antioxidants, supportive care for the leukemic patient experiencing complications from chemotherapy, palliative care for termination of those with leukemia, pharmacometrics using computational modeling to support drug development in leukemia, and future agents that are in clinical trials in our fight against leukemia. Reputable books, journals, monograms, clinical trials, and other resources were used to provide up-to-date medical information useful to assist healthcare professionals in the management of leukemia. Frontiers in Leukemia Pharmacotherapy is an excellent resource for curious healthcare professionals involved in the care of leukemic disorders.
(Imprint: Nova Medicine and Health)

Preface

Chapter 1. Overview of Acute and Chronic Leukemia
(Lunawati L. Bennett, MS, PhD, PharmD, Union University, College of Pharmacy, Jackson, TN, US)

Chapter 2. Molecular and Genetic Bases of Acute Leukemia
(Lunawati Bennett, PharmD, PhD, and Qingyu S Zhou, PhD, Union University, College of Pharmacy, Jackson, TN, US, and others)

Chapter 3. Molecular and Genetic Bases of Chronic Leukemia
(Qingyu Stephanie Zhou, PhD, University of South Florida, College of Pharmacy, Tampa, FL, US)

Chapter 4. Leukemia Pharmacology
(Lunawati Bennett, PhD. PharmD, Union University, College of Pharmacy, Jackson, TN, US)

Chapter 5. The Role of Tyrosine Kinase Inhibitors in Leukemia
(Michelle D. Lesé PharmD, Former Palm Beach Atlantic University School of Pharmacy Faculty, FL, US)

Chapter 6. Myelodysplastic Syndrome
(Zachery R. Halford, PharmD, Union University, College of Pharmacy, Jackson, TN, US)

Chapter 7. Acute Myeloid Leukemia
(Zachery R. Halford, PharmD, and Heath McLean, Union University, College of Pharmacy, Jackson, TN, US)

Chapter 8. Acute Lymphoblastic Leukemia
(Zachery R. Halford, PharmD, Union University, College of Pharmacy, Jackson, TN, US)

Chapter 9. Acute Promyelocytic Leukemia
(Zachery R. Halford, PharmD, Union University, College of Pharmacy, Jackson, TN, US)

Chapter 10. Chronic Myeloid Leukemia
(Zachery R. Halford, PharmD, and Elizabeth Sykes, Union University, College of Pharmacy, Jackson, TN, US)

Chapter 11. Chronic Lymphocytic Leukemia
(Zachery R. Halford, PharmD, Union University, College of Pharmacy, Jackson, TN, US)

Chapter 12. Pediatric Acute Myeloid Leukemia
(Zachery R. Halford, PharmD, Union University, College of Pharmacy, Jackson, TN, US)

Chapter 13. Pediatric Acute Lymphoblastic Leukemia
(Zachery R. Halford, PharmD, and Danya Horchi, Union University, College of Pharmacy, Jackson, TN, US)

Chapter 14. Metastasis in Leukemia
(Ifeoluwa Babatunde, PharmD, Case Western Reserve University, Cleveland, OH, US)

Chapter 15. Redox Homeostasis in Leukemia
(Lunawati Bennett, PhD, PharmD, Union University, School of Pharmacy, Jackson, TN)

Chapter 16. Supportive Care in Leukemia
(Lunawati Bennett, PhD, PharmD, Union University, College of Pharmacy, Jackson, TN, US)

Chapter 17. Palliative Care in Leukemia
(Emily P. Brand, Pharm.D, Union University College of Pharmacy, Jackson, TN, US)

Chapter 18. Pharmacometric in Leukemia
(Mitali Gaurav, Joel S. Owen and Andrew Castleman, Union University School of Pharmacy, Jackson, Tennessee, US, US)

Chapter 19. Future Chemotherapy
(Lunawati Bennett, PhD, PharmD, Union University, College of Pharmacy, Jackson, TN, US)

Index

“It was refreshing to read a work that is outside my specialty and be able to follow along without having to stop and look up every other word. It was engaging, informative, and right to the point. I loved how it was scholarly, yet personal, using language like “people,” “children,” and “pediatric,” reminding me that we’re not just talking about numbers and patients, but people, just like the ones I love in my family. This subject deserves our attention.” - Justin A. Brown, D.C.

“As a nurse professional, I highly recommend this book to increase patient knowledge. The book provides an awareness of information to observe and monitor to promote the highest quality of life for the patient. As health care staff, we need to keep educating patients so they can make the best-informed decisions regarding their care. This book will be that support.” - Susan Prince, RN Nurse Manager

“This book is an excellent example of scientific researchers and clinical practitioners working together to provide an overview of leukemias and their management.” - George DeMaagd, Pharm.D., BCPS

“An excellent resource for doctors, patients, and caregivers. Enlightening and clear descriptions of end of life processes, which help caregivers with a realistic and compassionate understanding, related to stages of care.” - Cynthia Konieczny, Psy.D.

“This book reviews the main aspects of leukemia, delving into interesting topics, such as the biology of different diseases and their possible therapeutic options.” - Adrian Montano, MSc.

“A concise, yet comprehensive, overview of a challenging range of topics related to the overview and treatment for leukemias. This book is an excellent resource, not only for clinicians actively involved with treating leukemias, but for all medical professionals, students, and patients as well.” - Christopher Elder, Pharm.D., BCOP

"This book provides a thorough insight to the disease and an understanding of pharmacologic treatment regimes. It presents the information in an easy to understand format and is a resource to those studying or dealing with the disease." - Dawn Hinson, RN, BSN, CCM, HCSA

“This book gives a detailed insight into various causations of different leukemias and lists therapies that work at various sites of the genetic and chromosomal aberrations that lead to these diseases and thus suggests potential treatments and possible cures for these conditions.” - R.W. Dunavant, MD

Keywords: Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myeloid Leukemia, Chronic Lymphoblastic Leukemia, Acute Promyelocytic Leukemia, Myelodysplastic Leukemia, Pediatric Acute Myeloid Leukemia, Pediatric Acute Lymphoblastic Leukemia, Redox Homeostasis in Leukemia, Metastasis in Leukemia, Supportive and Palliative Care in Leukemia, Pharmacometrics in Leukemia, Future and Novel Leukemia Pharmacotherapy

Audience: Physicians, pharmacists, nurses, other health care professionals, family member with an interest in serving and understanding patients with leukemia.

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