Focus on Systems Theory Research

Manuel F. Casanova (Editor)
University of South Carolina School of Medicine Greenville

Ioan Opris (Editor)
University of Miami, Miller School of Medicine, Miami, FL

Series: Mathematics Research Developments
BISAC: MAT000000




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This book offers a multidisciplinary approach to systems theory, investigating its general principles, mathematical models, and applications in health sciences. It describes how leaders in the field have made a transition from equations and models to dilemmas faced in the real world. This book is meant to simplify our understanding of disparate hierarchical and complex open systems in the world by making us aware of patterns of action among its components. These interactions lead to cascading effects within the system which end up changing it as a whole.

This self-organization often leads to unpredictable results transforming the system, or integrating the same, into a still more complex system. These results, not necessarily the ones originally sought by their organizers, may offer the system the best opportunity for sustainable and adaptive growth. In the end, readers of this book will gain a basic understanding of systems theory, its application to natural and manmade processes, and how systems grow and equilibrate with their environment in order to continue functioning.


Chapter 1. Biases in the Process of Designing a System
(Helmut Nechansky, Nechansky - Engineering Efficiency, Vienna, Austria)

Chapter 2. Mathematical Theory of Reliability and Biological Robustness: Reliable Systems from Unreliable Elements
(Vitaly K. Koltover, Institute of Problems of Chemical Physics, Russian Academy of Sciences, Chernogolovka, Moscow, Russia)

Chapter 3. Quantum Models of Complex Systems
(Miroslav Svítek, Czech Technical University, Faculty of Transportation Sciences, Czech Technical University in Prague, Prague, Czech Republic)

Chapter 4. Model-Order Reduction with H2/H∞ Performance
(Salim Ibrir, Department of Electrical Engineering, King Fahd University of Petroleum and Minerals, Dhahran, Kingdom of Saudi Arabia)

Chapter 5. Systems Thinking in Health Care: From Theory to Implementation
(Sheuwen Chuang, Graduate Institute of Data Science, Taipei Medical University, Taiwan and Peter Howley, School of Mathematical and Physical Sciences / Statistics, The University of Newcastle, Australia)

Chapter 6. Applications of Genome-Scale Metabolic Models and Data Integration in Systems Medicine
(Ali Salehzadeh-Yazdi, Markus Wolfien and Olaf Wolkenhauer, Department of Systems Biology and Bioinformatics, University of Rostock, Rostock, Germany, and others)

Chapter 7. Reality is Hierarchically Organized: The Recursive Foundations of Living Systems and Beyond
(Patrick Connolly, PhD, Department of Counselling and Psychology, Hong Kong Shue Yan University, Hong Kong, China)

Chapter 8. New Directions in Occupational Roadway Safety Grounded in Complex Systems Theory and Simulation Modeling
(Michael Kenneth Lemke and Yorghos Apostolopoulos, Department of Kinesiology and Health Science, Stephen F. Austin State University, Nacogdoches, TX, US, and others)

Chapter 9. The Part-System Continuum in Medicine

(Patrick Finzer, Düsseldorf, Germany)

Chapter 10. Systems Theory and the Cerebral Cortex
(Manuel F. Casanova, MD, Ioan Opris, PhD, Estate M Sokhadze, PhD, and Emily L. Casanova, PhD, Department of Biomedical Sciences, University of South Carolina School of Medicine Greenville, Greenville, SC)

Chapter 11. From Quorum Sensing to Dynome through Mitochondria
(Jean Ciurea and Tatiana Ciurea, Clinical Emergency Hospital “Bagdasar Arseni”
Functional Neurosurgery Department, Bucharest, Romania)

Chapter 12. The Nutrition System and the Brain
(Cosmin Sonea and Ioan Opris, USAMV Bucharest, Romania)

Chapter 13. A Modular Approach to the Organization of Brain Functions
(Ioan Opris, Estate M. Sokhadze, Emily L. Casanova, Cosmin Sonea and Manuel F. Casanova, Department of Neurological Surgery, Miami Project to Cure Paralysis, University of Miami, Miller School of Medicine, Miami, Florida, US, and others)


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