Features of Pathogenesis and Treatment of the SARS-CoV-2 Infection

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Authors: A.V. Pechersky, V.I. Pechersky, O.V. Pecherskaya, and V.F. Semiglazov
Page Range: 65-72
Published in: Journal of Stem Cells, Volume 16 Issue 2-3 (2021)
ISSN: 1556-8539

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Table of Contents

The cause of death in patients with the SARS-CoV-2 infection, along with respiratory failure, is infectious-toxic shock, complicated by multiple organ failure. Under the development of systemic inflammatory response syndrome (SIRS), excessive formation of pro-inflammatory cytokines and thrombosis can lead to the death of the macroorganism. When signs of systemic inflammatory response syndrome (SIRS) appear, the administration of blood clotting enzyme inhibitors (heparin preparations) together with antiviral, antibacterial and detoxification therapy can prevent the development of disseminated intravascular coagulation (DIC) caused by intoxication and the immune system’s response to microbial/viral antigens, through virus-altered antigens of its own tissues.

Keywords: SARS-CoV-2 infection, SIRS, immune system, regeneration