Table of Contents
Fanconi Anemia Clinical and Genetic Heterogeneity
(Adriana Zatterale, Head Emeritus, Genetics Department, ASL Napoli 1, Naples, Italy)
Chromosome Instability in Fanconi Anemia. Can it Be Mitigated by Antioxidant Small Molecules?
(Beatriz Porto, Filipa Ponte, Laboratory of Cytogenetics, ICBAS- Biomedical Institute Abel Salazar, University of Porto, Portugal)
Biochemical Grounds for “Crosslinker Sensitivity”: What Have we Learned from Pharmacology?
(Giovanni Pagano, Marco d’Ischia, Federico V. Pallardó, Italian National Cancer Institute, CROM, Italy, and others)
Involvement of Mitochondria in the Pathology of Fanconi Anemia
(Pavithra Shyamsunder, Rama S. Verma, Sudit S. Mukhopadhyay, Alex Lyakhovich, Stem cell and Molecular biology Laboratory, Department of Biotechnology, Indian Institute of Technology Madras, Chennai, India, and others)
Aldehydes as Markers of Redox Imbalance in Fanconi Anemia and in Other Oxidative Stress-Related Disorders
(Paola Manini and Marco d’Ischia, Department of Chemical Sciences, University of Naples Federico II, Naples, Italy)
Role of Glutathione and Other Antioxidant Related Mechanisms in Fanconi Anemia
(José Luis García Giménez, Carlos Romá-Mateo, Federico V. Pallardó, Department of Physiology, Faculty of Medicine and Dentistry, University of Valencia, Spain)
Proinflammatory Cytokines as Mediators of Oxidative Stress in Fanconi Anemia
(Annarita Aiello Talamanca, Giuseppe Castello, National Cancer Institute “Fondazione Pascale”, CROM Laboratory, Naples, Italy)
Need for in Vivo Characterization of Oxidative Stress and Mitochondrial Dysfunction in Fanconi Anemia Patients
(Giovanni Pagano and Luca Tiano, Italian National Cancer Institute, CROM, Mercogliano, Italy, and others)
Audience: Apart from their relevance in Fanconi Anemia, the subjects of oxidative stress and mitochondrial dysfunction have mechanistic implications in broad-ranging pathologies. Thus, our book may raise interest in a number of specialized medical communities.