Eye Banking: Changing Face of Corneal Transplantation


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Series: Eye and Vision Research Developments
BISAC: MED064000

Until a few years ago, eye banks were only considered as centres for collecting and processing units of human donor eyes. However, eye banks in recent years have changed the process of current corneal transplantation. Although the very first corneal transplantation was conceptualized in the late 18th century, it has taken a century to develop methods and understand the role of human corneas in general. This book gives an insight of worldwide associations and their standard regulations in terms of corneal donations, processes and transplantations. The associations mainly include: Eye Bank Association of America, European Eye Bank Association and Eye Bank Association of Australia and New Zealand. This book also refers to some of the early stages of eye banking and current methods of preservation, including cold and organ culture storage.

The current eye banking scenario is changing dramatically in terms of tissue processing. Once, tissues were only collected, stored and shipped for transplantation to the surgeons. Now eye banks have advanced in developing techniques in collaboration with surgeons to introduce more reliable methods of transplantation. This includes standardization of methods such as DSAEK, UT-DSAEK, pre-loaded grafts and DMEK. Furthermore, this compilation describes different techniques of lamellar keratoplasty, such as anterior and posterior lamellar keratoplasties. Retrieving, storing, processing and transplantation of such lenticules are also discussed in this book. Posterior lamellar graft preparation for selective surgeries like DSAEK and Ultra-Thin DSAEK has been included with relevant clinical approaches. DMEK, which is currently taking corneal transplantation to a different level, has been reported with various graft preparation techniques. The role of eye banks in general for such preparation method is also examined. Additionally, the importance of microbiology in day to day care in the field of corneal transplantation and eye banks exists as a topic within these pages.

Eye banks are playing a major role and changing the face of corneal transplantation in terms of new research; whether it be graft preparation for surgeries, preservation, surgical tools, ready-to-use tissues or studying cornea in details using available research tissues, these methods are advancing the field. Eye banks play a major role in tissue selection and correct processing methods. Surgeons are provided with a validated tissue so it makes easier for them to follow the transplantation. Therefore, this book highlights the new concepts in the eye banking field with regards to the standards, regulations, retrieval, preservation and transplantation methods. All of these continue to help aid in the research and development of surgical processes and devices.
(Imprint: Nova Biomedical)

Table of Contents

Table of Contents


Eye Banking: An Overview
Mohit Parekh, Stefano Ferrari and Diego Ponzin (International Center for Ocular Physiopathology (ICOP), Fondazione Banca Degli Occhi Del Veneto, Venice, Italy)

The European Eye Bank Association – Current Standards and Regulations
(Jesper Hjortdal & Gary L.A. Jones, The Danish Cornea Bank, Aarhus University Hospital, Denmark, and other)

Standards of Eye Banking in USA
(Diego Ponzin, Davide Camposampiero, Bradley Tennant and David Glasser, Fondazione Banca degli Occhi del Veneto Onlus, Venice, Italy, and others)

Legislation, Medical Standards and Regulations for Eye Banking in Australia and New Zealand
(Graeme A Pollock and S Louise Moffatt, Lions Eye Donation Service, Centre for Eye Research Australia, The University of Melbourne, Melbourne, Australia, and other)

Anterior Lamellar Keratoplasty and Deep Anterior Lamellar Keratoplasty
(Luigi Fontana, Alfonso Iovieno, Antonio Moramarco, Ophthalmic Unit, Santa Maria Nuova Hospital – IRCCS, Reggio Emilia. University of Modena – Reggio Emilia, Italy)

Descemet Stripping Automated Endothelial Keratoplasty
(Augusto Pocobelli and Francesco Aiello, Department of Ophthalmology, S. Giovanni – Addolorata Hospital, Rome, Italy, and other)

Ultra-Thin Descemet’s Stripping Automated Endothelial Keratoplasty (UT-DSAEK)
(Iva Dekaris, University Eye Hospital ‘Svjetlost’, Zagreb, Croatia)
Free Download Available

Pre-Loaded Tissue for DSAEK/UT-DSAEK
(Alessandro Ruzza, Mohit Parekh, Hossein Elbadawy, Stefano Ferrari, Yoav Nahum, Cristina Bovone, Massimo Busin and Diego Ponzin, International Centre for Ocular Physiopathology (ICOP), Fondazione Banca degli Occhi del Veneto Onlus, Venice, Italy, and others)

Descemet Membrane Endothelial Keratoplasty (DMEK)
(Marc Muraine, CHU de Rouen, France)

An Eye Bank DMEK Tissue Preparation Program for Corneas Stored at 4°C
(Joshua D. Galloway, Christopher G. Stoeger, Jeffrey D. Holiman and Michael Straiko, Lions VisionGift, Portland, OR, USA, and other)
Free Download Available

No-Touch Stripping Donor Tissue Preparation for Descemet Membrane Endothelial Keratoplasty
(Esther A. Groeneveld-van Beek, Jessica T. Lie, Kristin Mangundap, Vincent J.A. Bourgonje, Marieke Bruinsma, Jacqueline van der Wees, Gerrit R.J. Melles, Netherlands Institute for Innovative Ocular Surgery, Rotterdam, The Netherlands, and others)

Pre-bubbled Tissues for Descemet Membrane Endothelial Keratoplasty
(Mohit Parekh, Zala Luznik, Alessandro Ruzza, Stefano Ferrari, Hossein Elbadawy, Gianni Salvalaio, Massimo Busin and Diego Ponzin, International Center for Ocular Physiopathology, Fondazione Banca Degli Occhi del Veneto Onlus, Mestre, Venice, Italy, and others)

Microbiology in Eye Banking
(Davide Camposampiero, Elisa Zanetti, M. Rodriguez Calvo de Mora, Stefano Grandesso, Fondazione Banca degli Occhi del Veneto, Venezia, Italy, and others)

Corneal Graft Quality Controls: Present and Future
(Gilles Thuret, Sophie Acquart, Aurélien Bernard, Thierry Lepine, Fabrice Cognasse and Philippe Gain, Corneal Graft Biology, Imaging and Engineering Laboratory (BiiGC), Jean Monnet University, Saint-Etienne, France and others)

Current State and Future Prospects in the Field of Eye Banking
(W John Armitage, Bristol Eye Bank, NHS Blood & Transplant, Bristol, UK, and other)



“The book is excellent. It provides a great international overview of corneal tissue banking. It highlights the changing face of eye banking with the advent of evolving corneal lamellar transplantation. The chapters read well together.” – Reviewed by Sajjad Ahmad, MB BS, FRCOphth, PhD, Senior Clinical Lecturer, University of Liverpool

The book is written for ophthalmologists and eye banks.

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