Estrogen Receptors: Structure, Functions and Clinical Aspects


George G Chen, Michael CF Tong, and CA van Hasselt (Editors)
Department of Otorhinolaryngology, Head and Neck Surgery , Faculty of Medicine, The Chinese University of Hong Kong, Shatin, NT, Hong Kong

Series: Endocrinology Research and Clinical Developments
BISAC: MED027000

This 8-chapter book is written by experts from China, Mexico, Portugal, United Kingdom and the United States of America. The book is focused on estrogen receptor structure, functions and clinical significance. Though we are unable to address all aspects of the estrogen receptors, we have analysed and discussed estrogen receptors or their isoforms in some major estrogen receptor-related disorders including cancers, endocrine diseases, respiratory diseases and obesity. The information provided by this book should aid our understanding the role of estrogen receptors in human diseases. This book will be of great value not only for clinicians interested in estrogen receptor-related diseases but also for basic scientists working in the field of estrogen receptors.

Table of Contents

Table of Contents


Chapter 1. The Role of Estrogen Receptors Alpha in Breast Carcinogenesis: An Overview
(Micaela Almeida, Mafalda Neto Soares, José Fonseca-Moutinho, MD, PhD, Ana Cristina Ramalhinho, PhD, Luiza Breitenfeld, PhD, CICS-UBI – Centro de Investigação em Ciências da Saúde, Universidade da Beira Interior, Covilhã, Portugal, and others)

Chapter 2. Molecular Mechanisms That Modulate the Activity of Estrogen Receptor Alpha in Breast Cancer
(Angeles C. Tecalco–Cruz, PhD, Marina Macías–Silva, PhD, and Josué O. Ramírez–Jarquín, PhD, Programa de Ciencias Genómicas, Universidad Autónoma de la Ciudad de México, UACM, and others)

Chapter 3. Clinical Relevance of Biomarkers in Oestrogen Receptor Positive Breast Cancer
(R. M. Parks and K. L. Cheung, DM, School of Medicine, University of Nottingham, Nottingham, UK)

Chapter 4. Estrogen Receptor Alpha: Structure, Functions and Clinical Aspects in Endocrine System
(Xuemin Zhao and Jing Li, PhD, MD, Department of Internal Medicine, Chengde Medical University, Chengde, P.R. China, and others)

Chapter 5. Estrogen Signaling Pathway in Lung Cancer and Its Impact on Therapy
(Vianey Rodriguez-Lara, PhD, Tissue and Cellular Biology Department, School of Medicine, Universidad Nacional Autonoma de México [UNAM], Mexico City, Mexico)

Chapter 6. Estrogen Receptor Structure: Expression and Role in Gender Differences of Airway Diseases
(Olga Carvalho, PhD, Institute of Histology and Embryology, Faculty of Medicine, University of Coimbra, Coimbra, Portugal)

Chapter 7. Estrogen Receptor Alpha 36 in Cancers
(Lingbin Xue, Alexander C. Vlantis, MD, Jason Y. K. Chan, MD, Qian Cao, Xianhai Zeng, Fang Ma, C. Andrew van Hasselt, MD, George G. Chen, PhD, and Michael C. F. Tong, MD, Department of Otorhinolaryngology, Head and Neck Surgery, Chinese University of Hong Kong [CUHK], Prince of Wales Hospital, Shatin, NT, Hong Kong, China, and others)

Chapter 8. Estrogen Receptors and Obesity, with Focus on Adipose Tissues
(Arvand Asghari and Michihisa Umetani, PhD, Center for Nuclear Receptors and Cell Signaling, University of Houston, Houston, TX, US, and others)


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