Estradiol: Synthesis, Functions and Effectiveness


Lindsey Henderson (Editor)

Series: Human Reproductive System – Anatomy, Roles and Disorders
BISAC: MED058170

Estrogens comprise a group of structurally related and hormonally active molecules derived from cholesterol. 17¦Â-estradiol (E2) is the most potent member of this group. In Chapter One, the authors summarize various aspects of estradiol signaling, with special emphasis in the fast action of the hormone. Chapter Two discusses estradiol signaling pathways and how deficiency of estrogen, in the postmenopausal period, would cause CVS diseases and the potential therapeutic effect of estrogen for preventing cardiovascular diseases in postmenopausal women. Chapter Three covers a project that was undertaken to obtain an unbiased survey of differential gene expression in the liver in response to estrogen, TAM, and RAL. (Imprint: Nova Biomedical)

Table of Contents

Table of Contents


Chapter 1. The Subcellular Localization and Physiological Roles of Estrogen Receptors ¦Á and ¦Â in Classical and Non-Classical Tissues
Luc¨ªa Pronsato, Anabela La Colla, Lorena Milanesi and Andrea Vasconsuelo (INBIOSUR, National University of the South-CONICET, Bahia Blanca, Argentina)

Chapter 2. The Protective Effects of the Primary Female Sex Hormone Estradiol
Mohamed Abdel Aleem Haidara, Milan Obradovic, Emina Sudar-Milovanovic, Anastasija Panic, Milan Perovic, Desanka Cenic-Milosevic, Ema Aleksic, Jasmina Milic, Hanaa Zaki Yassin, Bahjat Al-Ani and Esma R. Isenovic (Department of Physiology, College of Medicine, King Khalid University, Abha, KSA, and others)

Chapter 3. Estrogen and Selective Estrogen Receptor Modulators that Regulate Differential Gene Expression in the Liver
Kathleen M. Eyster, Michelle Booze, Donis D. Drappeau, Olga Klinkova, M. Subeha Rahman and Connie Mark-Kappeler (Sanford School of Medicine, University of South Dakota, Division of Basic Biomedical Sciences, Vermillion, USA)


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