Essential Head and Neck Oncology and Surgery

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Maie A. St. John, MD, PhD, FACS – Department of Head and Neck Surgery, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA
Benjamin L. Judson, MD, MBA – Division of Otolaryngology, Department of Surgery, Yale School of Medicine, New Haven, CT, USA

Series: KJ Lee Essential Medicine Series
BISAC: MED062000; MED066000; MED081000
DOI: https://doi.org/10.52305/WVLB7531

This textbook presents a succinct yet comprehensive overview of the current essential topics in the multidisciplinary care of head and neck cancer patients. With each chapter written by experts in the many fields that comprise head and neck oncology and surgery, this compendium provides a unique, multidisciplinary perspective on the diagnosis and management of these patients. Information is presented in outline format to optimize the learning experience with multiple-choice questions to consolidate learning and practice guidelines to strengthen one’s grasp of the topics while presenting the opportunity for efficient reference. Finally, this textbook’s outline format, clear and concise language, and rich set of practice guidelines make it a trusted resource for nonmedical professionals hoping to learn more about head and neck cancer patients and their treatments.

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Table of Contents

Preface

Acknowledgements

Chapter 1. Oral Cavity, Pharynx, and Larynx Anatomy, Physiology, and other Basics
Patrick Ha, MD ¹ and Dennis Kraus, MD²
¹Department of Otolaryngology – Head and Neck Surgery, University of California, San Francisco, San Francisco, CA, USA
²Centura Cancer Care Network, Centura Health, Denver, CO, USA

Chapter 2. Temporal Bone and Skull Anatomy, Physiology, and other Basics
Francis Howard, MD¹ and Sujana Chandrasekhar, MD²
¹Department of Head and Neck Surgery & Communication Sciences, Duke University School of Medicine, Durham, NC, USA
²Partner, ENT & Allergy Associates, LLP, New York NY, USA

Chapter 3. Neck Spaces and Fascial Planes
Omar A. Karadaghy, MSCI, MD¹; Mia Jusufbegovic, MD²; Jeffrey M. Blumberg, MD, FACS²; Lisa and Shnayder, MD¹
¹Department of Otolaryngology-Head and Neck Surgery, University of Kansas Medical Center, Kansas City, MO, USA
²Department of Otolaryngology-Head and Neck Surgery, University of North Carolina Chapel Hill, Chapel Hill, NC, USA

Chapter 4. Thyroid and Parathyroid Glands
Amy Chen, MD¹ and Greg Randolph, MD²
¹Division of Otolaryngology—Head and Neck Surgery, Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA
²Thyroid/Parathyroid Endocrine Surgical Divisions, Harvard Medical School, Boston, MA, USA

Chapter 5. Salivary Gland Diseases
Dan Deschler, MD¹ and David Eisele, MD²
¹Department of Otolaryngology – Head and Neck Surgery, Harvard Medical School, Boston, MA, USA
²Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins Comprehensive Cancer Center, Baltimore, MD, USA

Chapter 6. Cysts and neoplasms of the Mandible and Maxilla
Brett Miles, MD¹ and Tara Aghaloo, MD²
¹Department of Otolaryngology, Head and Neck Surgery, Northwell Health Cancer Institute, New Hyde Park, NY, USA
²Section of Oral and Maxillofacial Surgery, Division of Diagnostic and Surgical Sciences, UCLA School of Dentistry, Los Angeles, CA, USA

Chapter 7. Carotid Body Tumors, Paragangliomas and Vascular Anomalies
Tammara Watts, MD¹ and Davud Sirjani, MD²
¹Department of Head and Neck Surgery & Communication Sciences, Duke University School of Medicine, Durham, NC, USA
²OHNS/Otolaryngology/Head & Neck Surgery, Stanford University, Stanford, CA, USA

Chapter8. Leukoplakia, Erythroplakia, and Premalignant Lesions
Hunter Archibald, MD; Ashok Jethwa, MD; and Frank Ondrey, MD, PhD, FACS
Department of Otolaryngology-Head and Neck Surgery, University of Minnesota, Minneapolis, MN, USA

Chapter 9, TNM Staging in Head and Neck Cancers
Michael H. Berger, MD¹; Jose P. Zevallos, MD, MPH²; and William B. Armstrong, MD¹
¹Department of Otolaryngology – Head and Neck Surgery, University of California Irvine, Irvine, CA, USA
²Department of Otolaryngology – Head and Neck Surgery, Washington University School of Medicine, St. Louis, MO, USA

Chapter 10. NCCN Head and Neck Guideline Overview
Saral Mehra, MD, MBA, FACS; and Babak Givi, MD
Head and Neck Surgery, Surgical Oncology, New York University Langone, New York, NY, USA

Chapter 11. Non-Melanoma Skin Cancers
Arielle Thal, MD¹; Thomas J. Ow, MD, MS, FACS¹; and Cecelia E. Schmalbach, MD, MSc, FACS²
¹Department of Otorhinolaryngology-Head and Neck Surgery, Montefiore Medical Center/Albert Einstein College of Medicine
²Department of Otolaryngology-Head and Neck Surgery, Temple University, Lewis Katz School of Medicine, Philadelphia, PA, USA

Chapter 12. Malignant Melanoma of the Head and Neck
Peter Yao, BSE¹,²; Kelly Malloy, MD³; and Luc GT Morris, MD, MSc²
¹Weill Cornell Medicine, New York, NY
²Head and Neck Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY
³Department of Otolaryngology, University of Michigan, Ann Arbor, MI, USA

Chapter 13. Tumors of the Oral Cavity and Pharynx
Richard Smith, MD, FACS¹ and Amy Hessel, MD²
¹Department of Otorhinolaryngology-Head and Neck Surgery, Montefiore-Einstein Cancer Center, Bronx, NY, USA
²Department of Head and Neck Surgery, Division of Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Chapter 14. HPV+ Oropharyngeal Cancers: Today and Tomorrow
Donovan Eu, MD, FAMS¹,²; Ameya A. Asarkar, MD, FACS³,⁴; and Jonathan Irish, MD, FRCS²
¹Department of Otolaryngology – Head Neck Surgery, National University Hospital System / National Cancer Institute, Singapore
²Department of Otolaryngology – Head and Neck Surgery/Surgical Oncology, Princess Margaret Cancer Centre/University Health Network, Toronto, Ontario, Canada
³Department of Otolaryngology/Head Neck Surgery, Ochsner-LSU Health, Shreveport, LA, USA
⁴Otolaryngology Section, Surgical ServiMelecace, Overton Brooks Veterans Affairs Medical Center, Shreveport, LA, USA

Chapter 15. Tumors of the Larynx, Hypopharynx, and Cervical Esophagus
Ameya A. Jategaonkar, MD¹; Timothy Blood, MD²; Dinesh K. Chhetri MD²; and David M. Cognetti MD¹
¹Department of Otolaryngology – Head and Neck Surgery, Thomas Jefferson University Hospital
²Department of Otolaryngology – Head and Neck Surgery, University of California, Los Angeles, Los Angeles, CA, USA

Chapter 16. Skull Base and Sinonasal Tumors
Janet Chao, MD¹; Thad Vickery, MD²; Michelle Chen, MD MHS³; R. Peter Manes, MD¹; and Daniel M. Beswick, MD²
¹Division of Otolaryngology—Head and Neck Surgery, Department of Surgery, Yale School of Medicine, New Haven, CT, USA
²Department of Otolaryngology—Head and Neck Surgery, UCLA School of Medicine, Los Angeles, CA, USA
³Division of Otolaryngology—Head and Neck Surgery, Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA

Chapter 17. Minimally Invasive Surgical Techniques for the Management of Head and Neck Cancers
Uma Duvvuri, MD¹ and Benjamin L. Judson, MD, MBA²
¹Department of Otolaryngology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
²Division of Otolaryngology, Department of Surgery, Yale School of Medicine, New Haven, CT, USA

Chapter 18. Neck Dissection and Management of the Neck
Samuel Auger, MD¹; Gina Jefferson, MD MPH FACS²; and Nishant Agrawal, MD¹
¹Department of Surgery, Section of Otolaryngology, University of Chicago Medicine, Chicago, IL, USA
²Department of Otolaryngology – Head and Neck Surgery, Thomas Jefferson University Hospital

Chapter 19. Head and Neck Reconstructive Surgery
Kristen A. Echanique, MD¹, Joseph B. Meleca, MD², Heather Edwards, MD³,  Michael Fritz, MD, FACS⁴, and Rhorie P. R. Kerr, MD
¹Department of Head and Neck Surgery, David Geffen School of Medicine, Los Angeles, CA, USA
²Department of Otolaryngology – Head and Neck Surgery, The University of Chicago Pritzker School of Medicine, Chicago, IL , USA
³Department of Otolaryngology, Boston University, Boston, MA, USA
⁴Facial Plastic and Microvascular Surgery, Cleveland Clinic, Cleveland, OH, USA

Chapter 20. Chemotherapy, Targeted Therapy, and Clinical Trials
Deborah J. Wong, MD, PhD¹ and Robert Haddad, MD²
¹Medical Oncology, Hematology, UCLA Santa Monica Medical Center and UCLA Medical Center, Santa Monica, CA, USA
²Dana Farber Cancer Institute, Boston, MA, USA

Chapter 21. Immunosurveillance and Immunotherapeutic Approaches in Head and Neck Cancer
Vikash Kansal, PhD¹; Robert L. Ferris, MD PhD²; and Nicole C. Schmitt, MD³
¹Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA, USA
²University of Pittsburgh School of Medicine, UPMC Hillman Cancer Center, Pittsburgh, PA, USA
³Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA, USA

Chapter 22. Targeted Radiation for Head and Neck Cancer: Specificity and De-escalation
James H. Laird, MD¹; Jie Deng, MD, PhD²; Sumi Sinha, MD³; Robert K. Chin, MD, PhD⁴; Sue S. Yom, MD, PhD², and Henry S. Park, MD, MPH⁵
¹Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT, USA
²Department of Radiation Oncology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA
³Department of Radiation Oncology, University of California San Francisco, San Francisco, CA, USA
⁴Department of Radiation Oncology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA
⁵Department of Otolaryngology, Head and Neck Surgery, Northwell Health Cancer Institute, New Hyde Park, NY, USA

Chapter 23. Surviving and Thriving:  Survivorship in the 21st Century
Jymirah R. S. Morris, MD¹; David Rapkin, PhD²; Marci L. Nilsen, PhD³; Jonas Johnson, MD⁴
¹University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA
²UCLA Head and Neck Surgery, University of California, Los Angeles, CA, USA
³Department of Acute and Tertiary Care, University of Pittsburgh, School of Nursing, Pittsburgh, PA, USA; Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
⁴Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA

Chapter 24. It Takes a Village: State of the Art Multidisciplinary Care
Kenric Tam, MD¹; Catherine T. Haring, MD²; Carol R. Bradford, MD¹; and Maie A. St. John, MD, PhD³
¹Department of Head and Neck Surgery, University of California, Los Angeles, Los Angeles, CA, USA
²Department of Otolaryngology—Head and Neck Surgery, The Ohio State University, Columbus, OH, USA
³Department of Head and Neck Surgery, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA

Index

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