Erythrocytes: Structure, Functions and Clinical Aspects

Katy Jorissen (Editor)

Series: Recent Advances in Hematology Research
BISAC: MED038000

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Volume 10

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Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick

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In Erythrocytes: Structure, Functions and Clinical Aspects, the authors summarize advances in human pluripotent stem cells-derived erythroid development and molecular regulatory mechanisms. This research may provide a new perspective on human embryo erythropoiesis and a possible treatment for some hematological diseases.

Erythrocytes are well equipped to carry out their functions due to a dynamic cell membrane, their inherent shape and lack of organelles and cytoplasmic viscosity. As such, the following section focusses on the causes of these modifications and their clinical implications.

As an example of complexity in research towards the development of erythrocyte membrane-based drug delivery systems starting from animal erythrocyte, morphological, biochemical and drug release profiles will be reviewed in the penultimate chapter.

The final chapter investigates the electrochemical behavior of erythrocytes at platinum, carbonaceous, and optically transparent electrodes via polarization and coulometric measurements. The order of magnitude of the quantity of electrons transferred between erythrocytes and electrodes was determined, and potential ranges showing indifference of the electrode toward red blood cells were identified.
(Imprint: Nova Medicine and Health)

Preface

Chapter 1. Research Advances in Erythroid Development from Human Pluripotent Stem Cells
(Yijin Chen, Bin Mao, Jia Feng, Yonggang Zhang, and Feng Ma, Institute of Blood Transfusion, Chinese Academy of Medical Sciences & Peking Union Medical College, CAMS & PUMC, Chengdu, China, and others)

Chapter 2. Erythrocyte Disorders: Causes and Clinical Outcomes
(R. Vani, PhD, and R. Soumya, PhD, Department of Biotechnology, JAIN, Deemed-to-be University, Bengaluru, Karnataka, India)

Chapter 3. Erythrocytes Membranes: Unique Constituent of Biological/Hybrid Drug Delivery Systems
(Ivana T. Drvenica, PhD, Ana Z. Stančić, Branko M. Bugarski, PhD, Ivana Pajic-Lijaković, PhD, Irina Maslovarić, PhD, and Vesna Lj. Ilić, PhD, Institute for Medical Research, and Faculty of Technology and Metallurgy, University of Belgrade, Belgrade, Serbia)

Chapter 4. Electrochemical Properties of Erythrocytes as a Reflection of Their Morphology and Interaction with Foreign Electrically Conductive Materials
(M.M. Goldin, I.V. Goroncharovskaya, A.K. Evseev, A.K. Shabanov, and S.S. Petrikov, Glen Oaks Community College, Centreville, MI, USA, and N.V. Sklifosovsky Research Institute of Emergency Medicine, Moscow, Russia)

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