Table of Contents
Preface
Section I. EPC Biological Function and Origin
Chapter 1. Advances in Endothelial Progenitor Cell Biology
Amankeldi A. Salybekov¹’²’³ and Takayuki Asahara²
¹Kidney Disease and Transplant Center, Shonan Kamakura General Hospital, Okamoto, Kamakura, Kanagawa, Japan
²Shonan Research Institute of Innovative Medicine, Shonan Kamakura General Hospital, Okamoto, Kamakura, Japan
³Qazaq Institute of Innovative Medicine, Nur-Sultan, Kazakhstan
Section II. EPC in Cardiovascular Diseases
Chapter 2. Diagnostic and Prognostic Potential of EPCs in Cardiovascular Diseases
Mehdi Hassanpour
Shonan Research Institute of Innovative Medicine, Shonan Kamakura General Hospital, Kamakura, Japan
Chapter 3. Epidemiology of Peripheral Artery Disease
Takayasu Ohtake¹’²’³ MD, PhD, and Shuzo Kobayashi²’³ , MD, PhD
1Regenerative Medicine, Center for Cell Therapy and Regenerative Medicine
2Shonan Research Institute of Innovative Medicine
3Kidney and Transplant Center, Shonan Kamakura General Hospital, Kamakura, Japan
Section III. EPC in Metabolic Diseases
Chapter 4. Endothelial Progenitors in Metabolic Diseases
Mattia Albiero¹’² and Gian Paolo Fadini¹’²
¹Department of Medicine, University of Padova, Padova, Italy
²Veneto Institute of Molecular Medicine, Experimental Diabetology Lab, Padova, Italy
Section IV. Clinical EPX Transplantation Trials
Chapter 5. Endothelial Progenitor Cell Therapy in Heart Disease – Pitfalls in Clinical Translation, Impact of Stem Cell Senescence, And Personalized Medicine by AI-Application
Gustav Steinhoff¹ and Markus Wolfien²
¹Emeritus Professor of Cardiac Surgery, Department Life, Light and Matter, University Rostock, Rostock, Germany
²University Rostock, Institute of Computer Science, Department of Systems Biology and Bioinformatics, Rostock, Germany
Chapter 6. EPC in Peripheral Arterial Diseases
Yasuyuki Fujita and Atsuhiko Kawamoto
Translational Research Center for Medical Innovation, Foundation for Biomedical Research and Innovation at Kobe, Kobe, Japan
Chapter 7. EPC in Kidney Diseases
Takayasu Ohtake¹’²’³ MD, PhD, and Shuzo Kobayashi²’³ MD, PhD
¹Regenerative Medicine, Center for Cell Therapy and Regenerative Medicine
²Shonan Research Institute of Innovative Medicine
³Kidney and Transplant Center, Shonan Kamakura General Hospital, Kamakura, Japan
Section V. EPC Derived Extracellular Vesicles
Chapter 8. Therapeutic Applications of Endothelial Progenitor Cell-Derived Extracellular Vesicles in Cardiovascular Diseases
Junjie Yang¹ and Jiacheng Sun²
¹Department of Anaesthesiology, University of Maryland School of Medicine, Baltimore, USA
²Department of Biomedical Engineering, University of Alabama at Birmingham, School of Medicine and School of Engineering, Birmingham, USA
Index