Endometrial Cancer: Risk Factors, Management and Prognosis

Simone Ferrero, M.D., Ph.D.
University of Genoa, Italy

Series: Cancer Etiology, Diagnosis and Treatments
BISAC: MED062000

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Endometrial cancer is the most common gynecological cancer and the sixth cause of cancer in developed countries. The findings that EC is a heterogeneous group of tumors with distinct risk factors and histopathological features, together with our improved understanding of its molecular mechanism has paved the way to the investigation of new surgical and medical therapies. The aim of this book is to give a complete overview on risk factors, pre-operative methods and management of endometrial cancer. The authors hope that this book will be a useful tool for any health provider involved in gynecological cancer care.

Preface

Chapter 1. Epidemiology and Risk Factors
(Chiara Bondi, MD, Fabio Barra, MD and Simone Ferrero, MD, PhD, Obstetrics and Gynecology, Dept. of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI), University of Genoa, Italy, and others)

Chapter 2. Molecular Pathology of Endometrial Carcinoma and Its Histopathological Correlations: Beyond a Dualistic Vision?
(Valerio Gaetano Vellone, MD, PhD, Leonardo Peñuela, MD, PhD, Riccardo Carbone, MD, Chiara Biatta, MD, Bruno Spina, MD, Fabio Barra, MD and Simone Ferrero, MD, PhD, Anatomic Pathology, Dept. of Integrated Diagnostic and Surgical Sciences (DISC), University of Genoa, Italy, and others)

Chapter 3. Histopathological Classification
(Leonardo Peñuela, MD, PhD, Michele Paudice, MD, Bruno Spina, MD, Fabio Barra, MD, Simone Ferrero, MD, PhD and Valerio Gaetano Vellone, MD, PhD, Anatomic Pathology, Dept. of Integrated Diagnostic and Surgical Sciences (DISC), University of Genoa, Italy, and others)

Chapter 4. Clinical Presentation and Transvaginal Ultrasound Assessment
(Fabio Barra, MD, Simone Ferrero, MD, PhD, Academic Unit of Obstetrics and Gynecology, Ospedale Policlinico San Martino, Largo R. Benzi, Genoa, Italy, and others)

Chapter 5. Radiological Assessment
(Ennio Biscaldi, MD, Fabio Barra, MD, Giulio Evangelisti, MD; Simone Ferrero, MD, PhD, Ospedale Galliera, Genoa, Italy, and others)

Chapter 6. Surgical Management of Early Stage Endometrial Cancer
(Andrea Tinelli, MD, PhD, Marilisa Scarciglia, MD, Giorgio Giorda, MD, Graziana Ronzino, MD, Donatella Russo, MD, Antonio Malvasi, MD, Ospan A. Mynbaev, MD, PhD and Samir A. Farghaly, MD, PhD, Gynecology and Obstetrics, “Vito Fazzi” Hospital, Lecce, Italy, and others)

Chapter 7. A Newer Perspective in the Surgical Approach to Endometrial Cancer: Sentinel Lymph Node Evaluation
(Giulio Evangelisti, MD, Fabio Barra, MD and Simone Ferrero, MD, PhD, Obstetrics and Gynecology, Dept. of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI), University of Genoa, Italy, and others)

Chapter 8. Adjuvant Therapy for High-Risk Endometrial Cancer
(Giuseppe Damiano, MD Fabio Barra, MD, Maria Laura Iaia, MD, Giacomo Bregni, MD, Simone Ferrero, MD, PhD AND Serafina Mammoliti, MD, Medical Oncology, Ospedale San Martino, Genova, Italy, and others)

Chapter 9. Management of Advanced Endometrial Cancer
(Elisa Zanardi, MD and Maria Maddalena Latocca, MD, Academic Unit of Medical Oncology, San Martino Polyclinic Hospital, Institute for Cancer Research and Treatment, Genoa, Italy, and others)

Chapter 10. The Role of Radiotherapy
(Romerai D’Amico, MD, Alessandro Colombo, MD and Ilaria Costanza Fumagalli, MD, Division of Radiotherapy, Hospital of Lecco, Lecco, Italy)

Chapter 11. Endometrial Cancer in Elderly Patients
(Valentino Martelli, MD, Fabio Barra, MD, Simone Ferrero, MD, PhD and Alessio Nencioni MD, Section of Geriatrics, Ospedale Policlinico San Martino, Largo R. Benzi, Genoa, Italy)

Chapter 12. New Perspectives with Targeted Drugs
(Fabio Barra, MD, Giulio Evangelisti, MD, Giuseppe Damiano, MD, Serafina Mammoliti, MD and Simone Ferrero, MD, PhD, Academic Unit of Obstetrics and Gynecology, Ospedale San Martino, Genoa, Italy)

Appendix I. Conservative Treatments for Endometrial Cancer
(Matteo Tantari, Fabio Barra and Simone Ferrero)

Appendix II. Brachyterapy Technique in Endometrial Cancer
(Elena Tornari, Camilla Satragno, Flavio Gianelli, Liliana Belgioia and Renzo Corvò)

Appendix III. Role of Palliative Radiation Therapy in Endometrial Cancer
(Liliana Belgioia, Camilla Satragno and Renzo Corvò)

Index

Keywords: Endometrial cancer; transvaginal ultrasound; hysterectomy

Audience: Gynecologist, radiologist, oncologist and physician interested in knowing the last updated information on endometrial cancer and its management.

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