Encyclopedia of Neurologic Disorders (2 Volume Set)


John G. Fitzpatrick (Editor)
Daniel J. Mulroy (Editor)

Series: Neurology – Laboratory and Clinical Research Developments, Neurodegenerative Diseases – Laboratory and Clinical Research
BISAC: MED056000

This book presents current research in the study of neurologic disorders. Topics discussed include oxidative stress-mediated neurodegeneration; mechanisms of the motoneuron stress response and its relevance in neurodegeneration; genetics and molecular biology of Alzheimer’s disease and frontotemporal lobar degeneration; molecular imaging and Parkinson’s disease; mitochondrion selective antioxidants as drug treatments for Alzheimer’s disease; the role of vitamins in vascular dementia and biofluid protein biomarkers for the diagnosis of vascular dementia. (Imprint: Nova Biomedical )

Table of Contents

Table of Contents


Oxidative Stress-Mediated Neurodegeneration: A Tale of Two Models
(Paul K. Y. Wong, Jeesun Kim, Soo Jin Kim, Xianghong Kuang, William S. Lynn, Department of Carcinogenesis, The University of Texas, MD Anderson Cancer Center, Science Park-Research Division, Smithville, Texas)

Mechanisms of the Motoneuron Stress Response and its Relevance in Neurodegeneration
(Mac B. Robinson, David J. Gifondorwa, Carol Milligan, Dept. of Neurobiology and Anatomy, Wake Forest University School of Medicine, Winston-Salem, North Carolina)

Methylene Blue Induces Mitochondrial Complex IV and Improves Cognitive Function and Grip Strength in Old Mice
(Afshin Gharib, Hani Atamna, Children’s Hospital Oakland Research Institute (CHORI), California, and others)

Receptor Specific Features of Excitotoxicity Induced Neurodegeneration
(Sergei M. Antonov, Dmitrii A. Sibarov, Sechenov Institute of Evolutionary Physiology and Biochemistry RAS, Saint-Petersburg, Russia)

Mitochondrial Uncoupling Proteins: Therapeutic Targets in Neurodegeneration?
(Susana Cardoso, Cristina Carvalho, Sónia Correia, Renato X. Santos, Maria S. Santos, Paula I. Moreira, Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal)

Targeting Caspases in Neonatal Hypoxic-Ischemic Brain Injury and Traumatic Brain Injury
(Xin Wang, Rachna Pandya, Jiemin Yao, He Ma, Jianmin Li, Laboratory of Neuroapoptosis Drug Discovery, Department of Neurosurgery, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA, and others)

Alterations in N-methyl-D-Aspartate (NMDA) Receptor Function and Potential Involvement in Anesthetic-Induced Neurodegeneration
(Cheng Wang, Xuan Zhang, Fang Liu, Merle G. Paule, William Slikker Jr., National Center for Toxicological Research, U.S. Food & Drug Administration, Jefferson, Arkansas)

Genetics and Molecular Biology of Alzheimer’s Disease and Frontotemporal Lobar Degeneration: Analogies and Differences
(Daniela Galimberti, Chiara Fenoglio, Elio Scarpini, Dept. of Neurological Sciences, “Dino Ferrari” Center, University of Milan, Milan, Italy)

The Cholinergic Neuron in Alzheimer’s Disease
(Christian Humpel, Celine Ullrich, Laboratory of Psychiatry and Exp. Alzheimers Research, Department of Psychiatry and Psychotherapy, Innsbruck Medical University, Austria)

Retinal Neurodegeneration is an Early Event in the Pathogenesis of Diabetic Retinopathy: Therapeutic Implications
(CIBERDEM, Instituto de Salud Carlos III), Barcelona, Spain) (Rafael Simó, Cristina Hernández, Diabetes and Metabolism Reseach Unit, Institut de Recerca Hospital Universitari Vall D’Hebron and CIBER for Diabetes and Associated Metabolic Diseases (CIBERDEM, Instituto de Salud Carlos III), Barcelona, Spain)

Molecular Imaging and Parkinson’s Disease
(Valentina Berti, Cristina Polito, Maria T. R. De Cristofaro, Alberto Pupi, Clinical Pathophysiology Department, Nuclear Medicine Unit, University of Florence, Florence, Italy)

Vascular Risk Factors, Brain Changes and Cognition: The Role of Metabolic Syndrome
(Bàrbara Segura, María Ángeles Jurado, Department of Psychiatry and Clinical Psychobiology, Faculty of Psychology, University of Barcelona, Barcelona, Spain, and others)

Oxidative Stress Induced Vascular Hypoperfusion, Mitochondrial Failure Are Missing Links for the Development of Alzheimer Disease
(Gjumrakch Aliev, Hector H. Palacios, Mark E. Obrenovich, Dmitry Gokhman, Valentin Bragin, Arturo Solís Herrera, School of Health Science and Healthcare Administration, University of Atlanta, Atlanta, Georgia, USA, and others)

GRK2 Overexpression is a Primary Hallmark of Vascular Hypoperfusion and Mitochondrial Lesions during Early Alzheimer Disease: New Target for Drug Treatment?
(Gjumrakch Aliev, Hector H. Palacios, Arturo Solís Herrera, Mark E. Obrenovich, School of Health Science and Healthcare Administration, University of Atlanta, Atlanta, Georgia, USA, and others)

Mitochondrion Selective Antioxidants as Drug Treatments for Alzheimer Disease
(Gjumrakch Aliev, Hector H. Palacios, Brandi Betts, Mark E. Obrenovich, Jerzy Leszek, Dmitry Gokhman, Valentin Bragin, Arturo Solís Herrera, Department of Health Science and Healthcare, University of Atlanta, Atlanta, Georgia, USA, and others)

What are the Roles of Vitamins in Vascular Dementia?
(Emel Koseoglu, Erciyes University, Medicine Faculty, Neurology Department, Kayseri, Turkey)

Vascular Factors on Alzheimer’s Disease
(Iulek Gorczevski, Andréa Heisler, Márcia Chaves, Matheus Roriz-Cruz, Divisions of Neurogeriatrics and Stroke, Department of Neurology, Federal University of ´Rio Grande do Sul´ State, Brazil)

New Concepts on Vascular Dementia
(Matheus Roriz-Cruz, Sheila O.C. Martins, Márcia L. Chaves
Divisions of Neurogeriatrics and Stroke, Department of Neurology,
Federal University of ‘Rio Grande do Sul’ state, Brazil)

Are Vascular, Alzheimer and Mixed Dementias Distinctive Entities?
(Nora Silvana Vigliecca, Consejo Nacional de Investigaciones Científicas y Técnicas de la Argentina, (CONICET) , Cordoba, Argentina, and others)

Biofluid Protein Biomarkers for the Diagnosis of Vascular Dementia
(Anja Hviid Simonsen, Gunhild Waldemar, Memory Disorders Research Group, Department of Neurology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark)

Apathy Associated With Subclinical Brain Ischemic Lesions and Vascular Risk Factors
(Hiroshi Yao, Yuki Takashima, Takahiro Mori, Manabu Hashimoto, Center for Emotional and Behavioral Disorders, National Hospital Organization Hizen Psychiatric Center, Saga, Japan)

Caudate Nucleus Volumes in the Leukoaraiosis and Disability in the Elderly Study (LADIS) – A Pilot Case-Control Study of Longitudinal Change
(Jeffrey Chee Leong Looi, Gabriela Spulber, Per Julin, Leif Svensson, Olof Lindberg, Lisa Botes, Yi Zhang, Eva Örndahl, Lars-Olof Wahlund, Research Centre for the Neurosciences of Ageing, Academic Unit of Psychological Medicine, Australian National University Medical School, The Canberra Hospital, Canberra, Australia, and others)

Neuroepidemiology of Vascular Dementia
(Masaaki Nakatsuka, Kenichi Meguro, Department of Geriatric Behavioral Neurology, Tohoku University Graduate School of Medicine, Sendai, Japan)

Validation of Two Short Dementia Screening Tests in Indonesia ^
(Eef Hogervorst, Fidiansjah Mursjid, Raden Irawati Ismail , Sabarinah Prasetyo, Martina Nasrun, Mochtar, Theresia Ninuk, Stephan Bandelow, Subarkah, Linda Kusdhany, and Tri Budi W. Rahardjo, Loughborough University, SSE&Health Sciences, United Kingdom,and others)

Cognitive Function and Hypertension: Pathophysiology and Mechanisms
(Rakesh Shukla, Kashif Hanif, Division of Pharmacology, Central Drug Research Institute, CSIR, Chattar Manzil, Lucknow, UP, India)

Investigating Grammatical Word Class Distinctions in Bilingual Aphasic Individuals
(Maria Kambanaros, Department of Speech and Language Therapy Technological Educational Institute of Patras, Greece)

The Role of the Right Hemisphere in Language Processing in Aphasic Patients
(Thomas Straube, Department of Biological and Clinical Psychology, Friedrich-Schiller-University, Germany)

Category and Letter Fluency in Primary Progressive Aphasia, Semantic Dementia, and Alzheimer’s Disease
(Cecile A. Marczinski, Northern Kentucky University)

Real-time Comprehension in Agrammatic Aphasia
(Petra B. Schumacher, Max Planck Institute for Psycholinguistics, Nijmegen, the Netherlands, and others)

Synthetic Expressions Do Not Standby
(Dieter G. Hillert, University of California, San Diego)

Lateralizing Value of Postictal Perseveration in Temporal Lobe Epilepsy
(Andras Fogarasi, Epilepsy Center, National Institute of Psychiatry and Neurology, Budapest, Hungary, and others)

Assessment and treatment of bilingual aphasia and bilingual anomia
(Patricia M. Roberts & Swathi Kiran)

Imaging Poststroke Aphasia
(A. Hillis, Baltimore, USA)


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