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With the emergence of AIDS in the early 1980s, concerns about the transmission of blood-borne pathogens began to grow in the workplace including in the healthcare setting. Responding to these concerns, the Centers for Disease Control and Prevention (CDC) in the USA have issued Universal Precautions, followed by Standard Precautions, aiming to protect healthcare workers (HCWs) from exposure to blood-borne pathogens. This new presents and discusses current research in the study of blood-borne exposure to pathogens, as well as prevention techniques to prevent against these infections. (Imprint: Nova)