Doxorubicin: Biosynthesis, Clinical Uses and Health Implications


Melinda Pache (Editor)

Series: Cancer Etiology, Diagnosis and Treatments
BISAC: MED062000

Doxorubicin is a classical but useful anti-tumor agent. It is used for the treatment of a variety of malignancies including solid tumors and leukemia due to its broad spectrum anti-tumor activity. It also has well known toxic side effects that must be minimized for its successful use clinically.

This book discusses intraperitoneal doxorubicin; preclinical characterization of the drug-delivery device DCBeads for transarterial chemoembolization of doxorubicin and nemorubicin; doxorubicin-induced cardiomyopathy; advanced therapies of doxorubicin by carrier of drug delivery system or combined food components; and prevention and management of cariotoxicity. (Imprint: Nova Biomedical )

Table of Contents

Table of Contents


Intraperitoneal Doxorubicin: Rationale, Pharmacokinetic Studies, and Clinical Results
(Paul H. Sugarbaker, Washington Cancer Institute, MedStar Washington Hospital Center, Washington, DC, USA)

Preclinical Characterization of the Drug-Delivery Device DCBeads™ for Transarterial Chemoembolization of Doxorubicin and Nemorubicin, a Methoxy-Morpholinyl Derivative
(Francesco Fiore, Olga Valota, Dario Ballinari, Federico Riccardi Sirtori, Maristella Colombo, Michela D’Antò, Cristina Geroni, Paolo Cappella, National Cancer Institute G. Pascale Fondation, Napoli, Italy, and others)

Doxorubicin-Induced Cardiomyopathy
(Xia Wang, Wei Han, Yan Yu, Jinzhou Zhu, Ruiyan Zhang, Laboratory of Regeneromics, School of Pharmacy, Shanghai Jiao Tong University, Shanghai, China, and others)

Advanced Therapies of Doxorubicin by Carrier of Drug Delivery System or Combined Food Components
(Yasuyuki Sadzuka, Professor, School of Pharmacy, Iwate Medical University, Iwate, Japan)

Prevention and Management of Cardiotoxicity, Nausea and Vomiting in Doxorubicin-Treated Breast Cancer Patients
(Snezana K. Bjelogrlic, Snezana Susnjar, Nebojsa Ninkovic, Department of Experimental Oncology, National Cancer Research Center, Belgrade, Serbia, and others)


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