Down Syndrome and Dementia. A Comprehensive and Historical Review

Vee Prasher, MD, PhD, MMedSci
Liverpool John Moores University, Birmingham, UK

Series: Disability Studies
BISAC: SOC029000



Volume 10

Issue 1

Volume 2

Volume 3

Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick


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It has been almost 150 years since Dr. Langdon Down first brought to our attention people with Down syndrome. Life expectancy, level of intellectual functioning, physical health, psychological health, social functioning, and integration into society are all issues that have markedly changed since 1866. The matter of aging in people with Down syndrome has consistently remained an area of intense interest. This book documents the most important published literature on the issue of dementia and Down syndrome published since Dr. Langdon Down’s momentous paper. Further, a number of publications from the general population which have had significant impact in the field of dementia and Down syndrome, and a number of papers in young adults and children with Down syndrome that have important implications for the aging population have been included. (Imprint: Nova Biomedical )

Preface to the First Edition

About the author


Chapter 1. Introduction

Chapter 2. Overview articles on dementia and Down syndrome

Chapter 3. epidemiological issues on dementia in Down syndrome

Chapter 4. Neuropathological issues on dementia in Down syndrome

Chapter 5. Clinical presentation of dementia in Down syndrome

Chapter 6. Neuropsychological assessments for dementia in Down syndrome

Chapter 7. Neuroimaging and neurophysiological issues on dementia in Down syndrome

Chapter 8. Biochemical abnormalities, dementia and Down syndrome

Chapter 9. Genetic association between dementia and Down syndrome

Chapter 10. Management and treatment of dementia in Down syndrome

Chapter 11. Services for adults with Down syndrome and dementia

Chapter 12. Textbook publications on Down syndrome and Dementia

Chapter 13. About the Disability Studies Book Series


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