Diffuse Large B-Cell Lymphoma (DLBCL): Symptoms, Treatment and Prognosis

Haipeng Shao
Department of Hematopathology and Laboratory Medicine, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA

Series: Cancer Etiology, Diagnosis and Treatments
BISAC: MED062000

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$190.00

Volume 10

Issue 1

Volume 2

Volume 3

Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick

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The diagnosis and treatment of Diffuse large B-cell lymphoma (DLBCL) have evolved significantly in the past decade. With advances in our understanding of DLBCL through the application of immunophenotypic, molecular cytogenetic analysis and clinical correlation, a growing number of discrete subtypes and entities of DLBCL have been recognized, along with improved prognostic stratification and treatment strategies. A simple diagnosis of DLBCL and standard chemotherapy are no longer appropriate for every individual patient anymore. Pathologists and practicing clinicians need to be familiar with current literature in order to achieve the best treatment of their patients. This book aims to provide the most up-to-date knowledge of the diagnosis, prognosis and treatment strategies of DLBCL.

Each chapter focuses on a different subject of DLBCL: pathology, prognosis, chemotherapy regimens and future directions, role of radiation therapy and hematopoietic stem cell transplant, and treatment strategies, as well as special considerations in the treatment of the most common subtypes of DLBCL. The authors are practicing physicians in major medical centers and university hospitals, and are familiar with the challenges of diagnosing and treating patients with DLBCL. The book is written for practicing physicians and provides practical information and advice for their daily practice. Residents, fellows and physicians in their early career development will also find the contents of this book useful for their education and board preparation. The authors hope that the material covered in this book will serve as a foundation for readers to keep up with future developments in this specific field of study.
(Imprint: Nova Biomedical)

Preface

Chapter 1
Pathologic Diagnosis and Prognostic Markers of Diffuse Large B-Cell Lymphoma
(Jinming Song, Ling Zhang, and Haipeng Shao, Department of Hematopathology and Laboratory Medicine, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA)

Chapter 2
Diffuse Large B-Cell Lymphoma: Diagnosis, Treatment and Prognosis
(Ashley T. Freeman and Steven I. Park, School of Medicine, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA)

Chapter 3
The Evolving Role of Radiation Therapy in the Management of Diffuse Large B-Cell Lymphoma
(Kamran A. Ahmed and Sungjune Kim, Department of Radiation Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA)

Chapter 4
Autologous and Allogeneic Hematopoietic Stem Cell Transplantation for Diffuse Large B-Cell Lymphoma
(Vijaya Raj Bhatt, Smith Giri, Guru Subramanian Guru Murthy, and R. Gregory Bociek, Division of Hematology-Oncology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, USA, and others)

Chapter 5
Primary Mediastinal Large B-Cell Lymphoma
(Andreas Saltos and Lubomir Sokol, Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA)

Chapter 6
Managing Diffuse Large B-Cell Lymphoma of the Central Nervous System
(Celeste M Bello, Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA)

Chapter 7
Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type
(Christa Roe, Frank Glass, Bela Kis, and Lubomir Sokol, Departments of Malignant Hematology, Department of Cutaneous Oncology, Department of Radiation Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA)

Chapter 8
Diffuse Large B-Cell Lymphoma Associated with Viral Infections and Immunodeficiency
(Julio C. Chavez, Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA)

Chapter 9
''Double Hit'' Diffuse Large B-Cell Lymphoma, from Biology to Clinical Outcome, Management and Future Direction
(Sarah Jewell, Shebli Atrash, Rebecca Levy, Appalanaidu Sasapu, Konstantinos Arnaoutakis, and Pooja Motwani, Division of Hematology/Oncology, Winthrop P Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA)

Index

“The authors have produced an updated and comprehensive survey of DLBCL pathologic and clinical information, with perspectives that will be appreciated by clinicians and translational researchers alike. In-depth descriptions of relevant clinical factors, including diagnosis and treatment strategies, paired with relevant clinical trial data, are synthesized into a thorough, informative, and useful guide for the practicing oncologist looking for evidence based and best practice strategies for treating DLBCL.” - Kristy L. Richards, Ph.D. M.D., Associate Professor, Hematology/Oncology, Weill Cornell Medicine, The Sandra and Edward Meyer Cancer Center, NY USA

The book is written for hematologists, oncologists, pathologists, nurses, clinical fellows, and residents. Patients diagnosis with diffuse large B-cell lymphoma will also find the information in the book useful for their treatment.

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