Dextran: Chemical Structure, Applications and Potential Side Effects

Garrett P. Figgs (Editor)

Series: Recent Trends in Biotechnology
BISAC: SCI010000



Volume 10

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Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick


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Dextran and dextran derivatives are widely used in solution to provide structure and function, e.g., colloidal stability, delivery of actives, viscoelasticity, to a variety of products. Underlying these functions are inter- and intra-molecular interactions that depend on the molecular characteristics of dextran (molecular weight, architecture, chemical modifications) and the type of solvent used (typically water, but may include salts, solutes and/or organic solvents).

Topics discussed in this compilation include dextran solution properties; dextran based nanoparticles for sustained drug delivery; gelation properties of whey protein and dextran conjugates obtained through maillard reaction; dextran based hydrogel and tissue adhesive agent and tissue engineering scaffold; application of DEAE-dextran to an efficient gene transfer system; conjugated dextran amines as intracellular tracers for visualizing and manipulating neurons; and effects of dextrans in the sugar industry. (Imprint: Nova)


Dextran Solution Properties
(Eleftheria Antoniou, Paschalis Alexandridis, Marina Tsianou, Department of Chemical and Biological Engineering, University at Buffalo, The State University of New York (SUNY), Buffalo, NY, USA, and others)

Dextran-Based Nanoparticles for Sustained Drug Delivery: Applications in Dry Eye Treatment and Cancer Therapy
(Mohit S. Verma, Shengyan Liu, Lyndon Jones, Frank X. Gu, Department of Chemical Engineering, University of Waterloo, Waterloo, Ontario, Canada, and others)

Gelation Properties of Whey Protein and Dextran Conjugates Obtained Through Maillard Reaction
(Ma. Julia Spotti, Amelia C. Rubiolo, Carlos R. Carrara, Instituto de Tecnología de Alimentos, Facultad de Ingeniería Química, Universidad Nacional del Litoral, Santa Fe, Argentina)

Dextran-Based Hydrogel as a Tissue Adhesive Agent and Tissue Engineering Scaffold
(Xiumei Mo, Liu Yuan and Hany A. EI-Hamshary, College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai, China and others)

Short Communication: Application of DEAE-Dextran to an Efficient Gene Transfer System
(Fumiaki Uchiumi, Steven Larsen, Sei-ichi Tanuma, Department of Gene Regulation, Tokyo University of Science, Noda, Chiba, Japan, and others)
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Conjugated Dextran Amines as Intracellular Tracers for Visualizing and Manipulating Neurons
(Joel C. Glover, NDEVOR, Dept. of Physiology, Institute of Basic Medical Sciences, University of Oslo Norwegian Center for Stem Cell Research, Oslo University Hospital)

Effects of Dextrans in the Sugar Industry
(Issam A. Khaddour, Department of Food Technology, Technological Faculty, Tishreen University, Tartous, Syria)


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