Cytokines: Roles and Therapeutic Implications

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Erik Krueger (Editor)

Series: Biochemistry Research Trends
BISAC: SCI007000

Cytokines are commonly referred to as the “language of intercellular interaction” since they send signals and commands to the cells to perform certain functions. In this compilation, the authors discuss how cytokines have demonstrated different patterns of production and interaction with other cytokines; therefore, cytokines can be considered as diagnostical markers and possible targets for therapeutic measures.
The authors illuminate the role of cytokines in different physiological circumstances affecting the onset, development and resolution of inflammation associated with inflammatory bowel disease.
The administration of cytokines as therapeutics has proven potential in the treatment of cancer and infectious and non-infectious disease.
The authors discuss cytokine profiles and their signaling in the autoimmune disease Guillain-Barre syndrome, and the potential of using this specific information for developing new therapeutic strategies.
The concluding study focuses on malignant breast cancer, the most common cancer in women worldwide. In recent decades, many advances have occurred in understanding the role of cytokines in this cancer, with several studies on new diagnostic and prognostic markers and their applications as a target in treatment.

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Table of Contents

Preface

Chapter 1. Current Views on the Role of Cytokines in the Regulation of Immune Reactivity and Their Role in Pathology of the Immune System
(Halyna Koval, Andrii Berbets and Oleksandr Yuzko, Bukovinian State Medical University, Chernivtsi, Ukraine)

Chapter 2. Therapeutic Implications of Cytokines in the Treatment of Inflammatory Bowel Disease
(Deepa S. Mandlik and Satish K. Mandlik, Department of Pharmacology, Poona College of Pharmacy, Bharat Vidyapeeth Deemed University, Pune, Maharashtra, India, and others)

Chapter 3. Therapeutic Role of Cytokines in Infectious and Non-Infectious Diseases
(Sambrinath Christopher, Betsy Ann Varghese, A. V. Sudarsan and E. Berla Thangam, Ph.D, Department of Biotechnology, School of Bioengineering, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu, India)

Chapter 4. Cytokines: Roles and Therapeutic Implications in Autoimmune Disease
(Justin K. Messex, Geou-Yarh Liou and Justin K. Messex, Center of Cancer Research and Therapeutic Development, Clark Atlanta University, Atlanta, GA, US)

Chapter 5. Cytokines in Breast Cancer
(Rosekeila Simões Nomelini, Izabella Cunha Campos, Mayara Rodrigues Andrade and Eddie Fernando Candido Murta, Research Institute of Oncology [IPON], Department of Gynecology and Obstetrics, Federal University of Triângulo Mineiro, Uberaba, MG, Brazil)

Index

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