Cutaneous T-Cell Lymphoma (CTCL): Clinical Features, Diagnosis and Treatment Options

Haipeng Shao (Editor)
Department of Hematopathology and Laboratory Medicine, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA

Series: Cancer Etiology, Diagnosis and Treatments
BISAC: MED062000

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Volume 10

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Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick

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Cutaneous T-cell lymphomas (CTCLs) are a heterogeneous group of Non-Hodgkin lymphomas with a variety of clinical presentation and outcomes. The diagnosis and treatment of CTCLs have evolved significantly with advances in our understanding of their pathogenesis and biological behaviors through immunophenotypic, molecular, and cytogenetic analysis and clinical correlation. The diagnosis and classification of CTCLs depend on integration of clinical presentation, histology, immunophenotype, molecular and/or cytogenetic findings. Accurate diagnosis and staging are essential for proper treatment and prognosis of the patients. The book Cutaneous T-Cell Lymphoma (CTCL): Clinical Features, Diagnosis and Treatment Options aims to provide the most up-to-date knowledge of the diagnosis, prognosis and treatment strategies of CTCL. Each chapter focuses on a different aspect of CTCL: clinical presentation, pathology, therapeutic options, role of radiation therapy, and in-depth discussion of the specific subtypes of CTCL classified under the most recent World Health Organization (WHO) classification of lymphoid neoplasms. The authors are practicing physicians in major medical centers and university hospitals, and are familiar with the challenges of diagnosing and treating patients with CTCL. The book is written for the practicing physicians and provides practical information and advice for their daily practice. Residents, fellows and other trainees will also find the contents of this book useful for their education and board preparation. The authors hope that the material covered in this book will serve as a foundation for the readers to keep up with future developments in the field. (Imprint: Nova Biomedical)

Preface

Chapter 1. Introduction to Cutaneous T-Cell Lymphoma
Florence Nappi, Neil Alan Fenske, Frank L Glass and Lucia Seminario-Vidal1 (University of South Florida, Tampa, FL, US, and others)

Chapter 2. Flow Cytometry in Cutaneous T-Cell Lymphomas
Pedro Horna (Division of Hematopathology, Mayo Clinic, Rochester, MN)

Chapter 3. The Cytogenetic and Molecular Landscape of Mycosis Fungoides and Sézary Syndrome
Pedro Horna (Division of Hematopathology, Mayo Clinic, Rochester, MN)

Chapter 4. Treatment of Cutaneous T-Cell Lymphoma
Facundo E. Stingo, Christa Roe and Lubomir Sokol (Departments of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, US)

Chapter 5. Management of Cutaneous T-Cell Lymphomas with Localized and Total Skin Electron Beam Radiotherapy
G. Daniel Grass, Kamran A. Ahmed and Sungjune Kim (Department of Radiation Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, US)

Chapter 6. Diagnosis, Prognosis and Genetic Features of Mycosis Fungoides and Sézary Syndrome
Xiaohui Zhang (Department of Hematopathology and Laboratory Medicine, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, US)

Chapter 7. Primary Cutaneous CD30+ T-Cell Lymphoproliferative Disorders
Hailing Zhang and Jinming Song (Department of Hematopathology and Laboratory Medicine, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, US)

Chapter 8. Indolent Primary Cutaneous T-Cell Lymphoproliferative Disorders
Haipeng Shao (Department of Hematopathology and Laboratory Medicine, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, US)

Chapter 9. Subcutaneous Panniculitis-like T-Cell Lymphoma
Jerry T. Wong, Shiraz Fidai, Joo Y. Song and Girish Venkataraman (Department of Pathology, The University of Chicago, Chicago, IL, US, and others)

Chapter 10. Primary Cutaneous Gamma-Delta T-Cell Lymphoma
Joo Y. Song (City of Hope National Medical Center, Department of Pathology, Duarte, CA, US)

Chapter 11. Primary Cutaneous CD8+ Aggressive Epidermotropic Cytotoxic T-Cell Lymphoma
Todd Rickett, Girish Venkataraman and Farah Abdulla (The University of Chicago, Chicago, IL, US)

Chapter 12. Cutaneous Extranodal Natural Killer/T-Cell Lymphoma, Nasal Type
Xueyan Chen, Sahr Syed, Girish Venkataraman and Lorinda Soma (Department of Laboratory Medicine, University of Washington, Seattle, WA, US, and others)

Chapter 13. Secondary Cutaneous T-Cell Lymphomas
Afshan Idrees and Haipeng Shao (Department of Hematopathology and Laboratory Medicine, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, US)

Chapter 14. Blastic Plasmacytoid Dendritic Cell Neoplasm: An Unforgettable Entity in the Differential Diagnosis of Cutaneous T-Cell Lymphomas (pp. 229-262)
Tania Mendoza and Ling Zhang (Department of Hematopathology and Laboratory Medicine, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, US)

Chapter 15. Mimics of Cutaneous T-Cell Lymphoma
Maria Deschaine and Jane Messina (Department of Anatomic Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, US)

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