Cutaneous Scars: Biology, Clinics and Management

Berna Aksoy (Editor)
Assoc. Professor, Chief, Department of Dermatology, Faculty of Medicine, Bahcesehir University, Istanbul, Turkey

Hasan Mete Aksoy (Editor)
Assist. Professor, Department of Plastic, Reconstructive and Aesthetic Surgery, Faculty of Medicine, Bahcesehir University, Istanbul, Turkey

Aslı Tatlıparmak (Editor)
Assist. Professor, Department of Dermatology, Faculty of Medicine, Bahcesehir University, Istanbul, Turkey

Erol Koç
Professor, Medicalpark Hospital, Clinic of Dermatology and Cosmetology, Ankara, Turkey

Series: New Developments in Medical Research
BISAC: MED017000

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Any cutaneous insult results in wound healing and wound healing results in formation of a scar. Human cutaneous scars represent a very important problem in clinical practice. Human cutaneous scars cause both cosmetic and medical problems in people who have them. There are various types of human cutaneous scars: physiologic normotrophic scars, atrophic scars, and proliferative scars. Additionally, there are scar complications that physicians must deal with. Scar complications include unstable scars, contractures and even development of malignancy at worst. Treatment of scars is also challenging especially in case of development of abnormal scars.

Human cutaneous scars have various aspects of interest such as biology, clinical significance, patient perspective, prevention, and treatment. There are various preclinical models for studying them. Scarless healing is another item of interest that is observed in fetal wound healing and in some animals. There are various studies specifically examining the biology and the treatment of proliferative scars. The cutaneous scars are very common so every physician will face a cutaneous scar-related problem in his/her medical practice. The significance is indicated by the frequency of burn injury and traffic accidents and by the importance of incision scars for any surgeon.
The editors of this book have enormous experience in the clinical management of human cutaneous scars.

The editors also studied the biology of abnormal scarring by developing new animal models. The editors also have performed clinical studies to increase therapeutic options for the treatment of abnormal scars. In this hardcover book, the aim is to examine human cutaneous scars in every aspect: historical aspects, clinical significance, biology, laboratory and animal models, histopathology, scarless healing, scar complications, and treatment. In this book, all the available treatment methods are examined in detail.
(Imprint: Nova Medicine and Health)

Dedication

Preface

Chapter 1. Introduction and Historical Perspectives
(F. Elif Yildirim, Department of Dermatology, Faculty of Medicine, SANKO University, Gaziantep, Turkey)

Chapter 2. The Significance of Scars: Patient and Clinician Perspectives
(Emin Ozlu, and Ayse S. Karadag, Department of Dermatology, Faculty of Medicine, Duzce University, Duzce, Turkey, and others)

Chapter 3. Biology of Wound Healing and Scar Formation
(Timuçin Avsar, PhD, Alihan Sursal, Berfu Nur Yigit, and Deniz Altunsu, Department of Medical Biology, Bahcesehir University, School of Medicine, Istanbul, Turkey, and others)

Chapter 4. The Biology of Proliferative Scars: Hypertrophic Scar and Keloids
(Ezgi Ozkur, Department of Dermatology, Health Science University, Şişli Etfal Training and Research Hospital, Istanbul, Turkey)

Chapter 5. Biology of Scar Complications: Unstable Scars, Contractures and Scar Malignancies
(Zehra Asiran Serdar, and Ezgi Aktas Karabay, Department of Dermatology, Faculty of Medicine, Bahcesehir University, Istanbul, Turkey)

Chapter 6. Models for Wound Healing and Scarring
(Berna Aksoy, Department of Dermatology, Faculty of Medicine, Bahcesehir University, Istanbul, Turkey)

Chapter 7. Histopathology of Cutaneous Scars
(Duru Onan, Department of Dermatology, University of Health Sciences, Ankara Numune Training and Research Hospital, Ankara, Turkey)

Chapter 8. Scarless Healing and Future Directions
(Nilgun Senturk, Department of Dermatology, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey)

Chapter 9. Clinical Aspects of Scars
(Zehra Asiran Serdar, and Neslihan Fisek Izci, Department of Dermatology, Faculty of Medicine, Bahçeşehir University, Istanbul, Turkey)

Chapter 10. Clinical Aspects of Atrophic Scars: Surgical, Post-Acne and Striae
(Aysun Sikar Akturk, Department of Dermatology, Faculty of Medicine, Kocaeli University, Kocaeli, Turkey)

Chapter 11. Clinical Aspects of Proliferative Scars: Hypertrophic Scar and Keloids
(Elif Yildirim, Department of Dermatology, Faculty of Medicine, SANKO University, Gaziantep, Turkey)

Chapter 12. Scar Scales
(Ilkay Ozer, and Meltem Onder, Department of Dermatology and Venerology, Meram Faculty of Medicine, Necmettin Erbakan University, Konya, Turkey, and others)

Chapter 13. Acne Scar Scales
(Neslihan Fisek Izci, Department of Dermatology, Faculty of Medicine,Bahçeşehir University, Istanbul, Turkey)

Chapter 14. Dermatoses Developing on Scar Tissue
(Mualla Polat, and Tekden Karapinar, Department of Dermatology, Faculty of Medicine, Bolu Abant Izzet Baysal University, Bolu, Turkey)

Chapter 15. Complications of Cutaneous Scarring: Clinical Aspects
(Evren Odyakmaz Demirsoy, and Emrah K. Yasar, Deparment of Dermatology and Department of Plastic and Reconstructive Surgery, Faculty of Medicine, Kocaeli University, Kocaeli, Turkey)

Chapter 16. Course and Prognosis
(Ezgi Ozkur, Department of Dermatology, Health Science University, Sisli Etfal Training and Research Hospital, Istanbul, Turkey)

Chapter 17. Prevention of Abnormal Scarring
(Hilal Gokalp, and Zekayi Kutlubay, Department of Dermatology, Faculty of Medicine, Istinye University, Istanbul, Turkey, and others)

Chapter 18. Biophysical Therapeutics
(Zeynep Topkarci, Department of Dermatology, Health Science University, Bakirkoy Dr Sadi Konuk Training and Research Hospital, Istanbul, Turkey)

Chapter 19. Topical Medical Treatments
(Sevil Savas Erdogan, Department of Dermatology, Sultan Abdulhamit Han Training and Research Hospital, Istanbul, Turkey)

Chapter 20. Intralesional Treatments
(Asli Hapa, Dermatology Clinic, University of Health Sciences, Bozyaka Research and Training Hospital, Izmir, Turkey)

Chapter 21. Systemic Medical Treatments
(Sibel Dogan, Department of Dermatology and Venereology, Faculty of Medicine, Hacettepe University, Ankara, Turkey)

Chapter 22. Scar Revision Surgery
(Atilla A. Eyuboglu, Andac Aykan, and Muhitdin Eski, Department of Plastic, Reconstructive and Aestetic Surgery, Memorial Bahcelievler Hospital, Istanbul, Turkey, and others)

Chapter 23. Surgical Treatment of Proliferative Scars
(H. Mete Aksoy, Department of Plastic, Reconstructive and Aesthetic Surgery, Faculty of Medicine, Bahcesehir University, Istanbul, Turkey)

Chapter 24. Laser Therapy of Cutaneous Scars
(G. Isil Kurmus, and Erol Koc, Department of Dermatology and Cosmetology, Medical Park Ankara Hospital, Ankara, Turkey)

Chapter 25. Other Treatments
(N. Burcu Ozturk, Specialist of Dermatology, Private Practice, Kocaeli, Turkey)

Chapter 26. Treatment of Acne Scars
(Asli Tatliparmak, Department of Dermatology, Bahçeşehir University, Istanbul, Turkey)

Chapter 27. Treatment of Striae
(G. Isil Kurmus, and Erol Koc, Department of Dermatology and Cosmetology, Medical Park Ankara Hospital, Ankara, Turkey)

Chapter 28. Hair Transplantation for Scars in Hair Bearing Skin
(Ekrem Civas, Dermatology Specialist, Private Civas Clinic, Ankara, Turkey)

About the Authors

About the Editors

Index

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