Corticosterone: Roles, Research and Insights

Jonathan Simmons (Editor)

Series: Biochemistry Research Trends
BISAC: SCI007000



Volume 10

Issue 1

Volume 2

Volume 3

Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick


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This book discusses the roles and provides new research and insights on the glucocorticoid known as corticosterone. Chapter One presents and discusses the mechanisms underlying the harmful effects of glucocorticoids in the pathophysiology of major depressive disorder. Chapter Two focuses on alterations of the brain serotonergic system induced by dysfunctions of the adrenal gland. Chapter Three highlights wild animal studies on glucocorticoids and discusses how they inform biomedical research. Chapter Four summarizes present knowledge about corticosterone regulation in rodents with special emphasis to stressor differences.


Chapter 1. Roles of Glucocorticoids in the Pathophysiology of Major Depression
Andiara E. Freitas, Fernanda N. Kaufmann, Manuella P. Kaster and Ana Lúcia S. Rodrigues (Department of Biochemistry, Center of Biological Sciences, Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil)

Chapter 2. Alterations of the Brain Serotonergic System Induced by Dysfunctions of the Adrenal Gland
Carmen Frias-Dominguez, René Drucker Colín and Stefan Mihailescu (Departmento de Fisiología, Facultad de Medicina, Instituto de Fisiología Celular Universidad Nacional Autónoma de México, Mexico DF, Mexico)

Chapter 3. Wild Animal Studies on Glucocorticoids and How They Can Inform Biomedical Research
Ryan J. Seddon and Diana K. Hews (Department of Biology, Indiana State University, Terre Haute, Indiana, USA)

Chapter 4. Regulation of Corticosterone Secretion in Rodents
Dóra Zelena (Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary)


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