Congenital Heart Disease: From Diagnosis to Treatment


Curtis Giguère (Editor)

Series: Cardiology Research and Clinical Developments
BISAC: MED010000

Congenital Heart Disease: From Diagnosis to Treatment opens with a review of the most common forms of congenital heart disease in pregnancy, outlines preconception counseling, discusses the associated morbidity and mortality of each lesion, and reviews current recommendations for the management of congenital heart disease in pregnancy.

Women with congenital heart disease represent over 50% of patients with cardiac disease in pregnancy today. Formerly characterized by high rates of maternal morbidity and mortality, the authors explore how advancements in medical management and surgical intervention are responsible for increasing numbers of women with congenital heart defects experiencing safe and successful pregnancies.

Additionally, the authors discuss cardiac resynchronization therapy in adults with congenital heart disease. Treatment in the setting of heart failure is challenging due to heterogeneity of the underlying anatomy and physiology, surgical scars, residual shunts and valvular dysfunction. Since donor hearts are scarce, worldwide interest has increased for the application of cardiac resynchronization therapy in this relatively young population.

This compilation goes on to discuss the four different types of atrial septal defects, categorized based on location and embryological development. While bicuspid aortic valve is the most common congenital heart anomaly in adults, atrial septal defects are not far behind, accounting for 10-15% of congenital heart disease.

In the penultimate study, the authors focus on the state of the liver in children with congenital heart disease and chronic heart failure. Congenital heart disease represented: ventricular septal defect – in 26,7% of patients, secondary atrial septal defect – in 24,4% of children, a double discharge of the main vessels of the right ventricle – in 15,6% of patients, common atrioventricular canal – at 15,6% of children, tetralogy of Fallot – at 11,1% of patients, etc.

The concluding study reviews the effects of high altitude effects on congenital heart disease in the Andean region, and in Ecuador as a study case. High-altitude hypoxia presents numerous challenges to human health, survival, and reproduction because of decreased oxygen availability brought on by lowered barometric pressure at high elevations.
(Imprint: Nova Medicine and Health)

Table of Contents

Table of Contents


Chapter 1. Congenital Heart Disease and Pregnancy
(Maeve K. Hopkins and Jeffrey A. Kuller, Maternal Fetal Medicine, University of Pennsyvlania, Philadelphia, PA, US, and others)

Chapter 2. Pregnancy Considerations in Women with Congenital Heart Disease
(Martina L. Badell, MD, and Brian Z. Druyan, MD, Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, GA, US)

Chapter 3. Cardiac Resynchronization Therapy in Adults with Congenital Heart Disease: Current State and Future Perspectives
(Rohit K. Kharbanda, Ad J.J.C. Bogers and Natasja M.S. de Groot, Department of Cardiology, Erasmus Medical Center, Rotterdam, the Netherlands, and others)

Chapter 4. Types, Presentation, and Management of Atrial Septal Defects in Adults
(Samantha Whitwell, Frank Han, MD, Michael McMullan, MD, and William Campbell, MD, University of Mississippi Medical Center, Jackson, MS, US)

Chapter 5. State of the Liver in Children with Congenital Heart Disease
(M. P. Lymarenko, Department of Pediatrics, Faculty of Internship and Postgraduate Education, Donetsk National Medical University M. Gorky, Ukraine)

Chapter 6. High Altitude and Congenital Heart Disease in Andean Highlands Populations: The Case of Ecuador
(Fabricio González-Andrade, Stephanie Michelena, Daniel Echeverría Espinosa and Gabriela Aguinaga Romero, Universidad Central del Ecuador, Facultad de Ciencias Médicas, Unidad de Medicina Traslacional, Iquique y Sodiro-Itchimbía, Quito, Ecuador, and others)


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