Click Chemistry: Approaches, Applications and Challenges

Yu Chen (Editor)
School of Materials Science and Engineering,
Beijing Institute of Technology, Beijing , China

Zong-Rui Tong (Editor)
School of Material Science and Engineering, Beijing Institute of Technology, Beijing, China

Series: Chemistry Research and Applications
BISAC: SCI013000

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Click chemistry, which is also referred to as linkage chemistry, dynamic, combinatorial chemistry or quick linking combinatorial chemistry describes the reaction that joins molecular fragments as simply, efficient and versatile as clicking a mouse. The two units with specific click structures can be linked by a click reaction no matter what is attached to the structure, and only the specific click structures can be joined. It emphasizes the development of new combinatorial chemistries on the basis of the synthesis of efficient and highly selective carbon-heteroatom bonds (C-X-C), and effectively prepares molecules with high diversity via these simple reactions. It significantly simplified and promoted the development of synthesis chemistry. Click chemistry has become one of the most useful and attractive synthetic strategies in many fields.

In this book, the definition of click chemistry is explained, the characteristics and types of click chemistry are introduced, and some specific reaction types are focused on. The progress for using click chemistry for the synthesis and functionalization of hydrogels, elastomers, surface modifications, membrane preparations, assemble polyaromatic structures, biomedical fields and optical sensing in biological analyses are described in detail. The problems and challenges for using click chemistry in different fields are analyzed. (Imprint: Nova)

Chapter 1. The Introduction of Click Chemistry Reaction
Chen Yu (School of Materials Science and Engineering, Beijing Institute of Technology, Beijing , China)

Chapter 2. Nitrile N-Oxide-Based Click Reactions Accompanying C-C Bond Formation
Yasuhito Koyama and Toshikazu Takata (Department of Biotechnology, Faculty of Engineering, Toyama Prefectural University, Kurokawa, Imizu, Toyama, Japan, and others)

Chapter 3. Bi-1,2,3-Triazoles: Synthesis and Perspectives
Ivette Santana-Martinez and Erick Cuevas-Yañez (Joint Center for Research in Sustainable Chemistry UAEM-UNAM, Autonomous State University of Mexico, Toluca, Estado de México, México)

Chapter 4. Click Chemistry of Natural Polymers
Yu-Tong Zhang, Zhu-Yun Li and Yu Chen (School of Materials Science and Engineering, Beijing Institute of Techology, Beijing, China)

Chapter 5. Synthesis and Functionalization of Hydrogel through “Click-Chemistry”
Mi-Heng Dong and Yu Chen (School of Materials Science and Engineering, Beijing Institute of Technology, Beijing, China, and others)

Chapter 6. Using of Click Chemistry for Elastomer
Ya-Lun Wang and Yu Chen (School of Materials Science and Engineering, Beijing Institute of Technology, Beijing, China)

Chapter 7. Surface Engineering of Porous Monoliths via Click Chemistry: Towards Functional Materials for Flow Chemistry Applications
Seydina Ibrahima Kebe, Hela Kammoun, Mohamed Guerrouache, Samia Mahouche-Chergui, Sabrina Belbekhouche, Benjamin Le Droumaguet, Yosra Dridi-Zrelli and Benjamin Carbonnier1 (University of Paris-Est, Thiais, France, and others)

Chapter 8. Click Chemistry for Membrane Preparation and Surface Modification
Zhu-Fang Hu, Jin Zhou and Hai-Yin Yu (College of Chemistry and Materials Science, Anhui Normal University, Wuhu, Anhui, China, and others)

Chapter 9. Copper-Mediated Click Chemistry Applications to Assemble Polyaromatic Structures
Celedonio M. Álvarez, Héctor Barbero, Sergio Ferrero (Faculty of Sciences, University of Valladloid, Valladolid, Spain)

Chapter 10. Application of Click Chemistry in Biomedical Fields
Chen Yu, Zhang Ying, Sun Xiaoyu and Yuan Jingjing (School of Materials Science and Engineering, Beijing Institute of Technology, Beijing , China)

Chapter 11. Click Chemistry: Optical Sensing in Biological Analysis
Suyan Qiua, Fang Luob, Linguang Luoa, Longhua Guob, Bin Qiub, Zhenyu Linb and Guonan Chenb (Institute for Quality & Safety and Standards of Agricultural Products Research, Jiangxi Academy of Agricultural Sciences, Nanchang, Jiangxi, China, and others)

Chapter 12. Telechilic Polybutadiene Solid Propellant Binders Based on ‘Çlick’ Chemistry Approach
S.Reshmi, E.Arunan and C.P.Reghunadhan Nair (Polymers and Special Chemicals Group, Vikram Sarabhai Space Centre, Kerala, India, and others)

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