Table of Contents

Preface

Chapter 1. Beta-Lactam Agents Serum Measurements by Liquid Chromatography to Evaluate Meropenem and Piperacillin Effectiveness in Septic Burn Adults with a Pharmacokinetic-Pharmacodynamic Approach
Leonard de Vinci Kanda Kupa¹, PhD, Vanessa Kasubeck de Souza¹, PhMs, Thais Vieira Camargo¹, PhMs, Claudia Garcia Messiano¹, PhMs, Ronaldo Morales Junior¹, PhD, Valentina Porta¹, PhD, Mauricio Yonamine², PhD, Beatriz Aparecida Passos Bismara Paranhos², PhD, Aline Sandré Gomides Abad³, BS, Gabriela Aparecida Ferreira³, BS, Edvaldo Vieira de Campos³, MD, Élson Mendes da Silva Junior³, MD, João Manoel da Silva Junior³, MD, Debora Cristina Sanches Pinto³, MD David de Souza Gomez³, MD, and Silvia Regina Cavani Jorge Santos¹, PhD
¹Clinical Pharmacokinetics Center, School of Pharmaceutical Sciences, University of Sao Paulo, Sao Paulo, Brazil
²Department of Clinical-Toxicology Analysis, Multi-User Laboratory of Analytical Center, School of Pharmaceutical Sciences, University of Sao Paulo, Sao Paulo, Brazil
³Plastic Surgery and Burns Division of Clinics Hospital, Surgery Department of Medical School, University of Sao Paulo, Sao Paulo, Brazil

Chapter 2. Preconcentration Strategies Coupled with Chromatographic Methods for the Determination of Organic Compounds
Raif İlktaç
Application and Research Center for Testing and Analysis, University of Ege, Bornova, İzmir, Turkey

Chapter 3. Bioanalytical Methods Based on Liquid Chromatography for the Therapeutic Drug Monitoring of Combined Therapies of Antibiotics in Pediatric Septic Major Burns
Silvia Regina Cavani Jorge Santos¹, PhD, Thais Vieira Camargo¹, MS, PhD, Leonard de Vinci Kanda Kupa¹, PhD, Ronaldo Morales Junior¹, PhD, Claudia Garcia Messiano¹, MS, Vanessa Kasubeck de Souza¹, MS, Frederico Ribeiro Pires¹, MD, Aline Sandre², BS, Gabriela Aparecida Ferreira², BS, Edvaldo Vieira de Campos², João Manoel da Silva Junior², MD, Débora Cristina Sanches Pinto², MD, and David de Souza Gomez², MD
¹Clinical Pharmacokinetics Center, University of Sao Paulo, Sao Paulo, Brazil
²Plastic Surgery and Burns Division of Clinics Hospital, Surgery Department of Medical School, University of Sao Paulo, Sao Paulo, Brazil

Chapter 4. Liquid Chromatography-Tandem Mass Spectrometry for Simultaneous Piperacillin-Meropenem Serum Measurements in Septic Burns for Effectiveness
Paschoalina Romano¹, PhD, Pérsio de Almeida Rezende Ebner¹, BS, Marc Yves Chalom¹, BS, Maria Severina dos Santos¹, BS, Marcio Santos Garcia¹, BS, Kupa Leonard de Vinci Kuppa Kanda², PhD, Nairo Massakazu Sumita¹, PhD, Nilo José Coêlho Duarte¹, MD, Aline Sandre, BS, Gabriela Aparecida Ferreira³ BS, Joao Manoel da Silva Junior³, MD, Thais Vieira de Camargo³, PhMS, Ronaldo Morales Junior³, David de Souza Gomez³, MD and Silvia Regina Cavani Jorge Santos³, PhD
¹Central Laboratory Division and Medical Investigation Laboratory (LIM 03) – Medical School, University of Sao Paulo (HCFMUSP)
²Medical investigation Laboratory (LIM 17), Medical School, University of Sao Paulo, Sao Paulo, Brazil

Chapter 5. A Brief Review of Chromatographic Methods for the Quantification of Favipiravir
I. M.Nandeesha^1, MSc, G.Nagalakshmi², PhD, K.Umesha³, PhD, B. C.Yallur¹, PhD, T. M.Veeresha⁴, PhD and D. H. Manjunatha⁵, PhD
¹Department of Chemistry, MS Ramaiah Institute of Technology, Bengaluru, Karnataka, India
²Department of forensic science, Soundarya Institute of management and Science, Bengaluru, Karnataka, India
³PG Department of Chemistry, Vijaya College, Bangalore, Karnataka, India
⁴Department of Chemistry, Vijayanagar College, Hosapete, Vijayanagara, Karnataka, India
⁵Deparment of Studies in Chemistry, Shivagangotri, Davangere University, Davangere, Karnataka, India

Chapter 6. Advances in Quantitative Liquid Chromatography-Mass Spectroscopy for Central Nervous System Melanocortin Hormone Quantification
Renée Onnainty¹, PhD, Guadalupe Herrera², PhD, and Gladys E. Granero¹, PhD
¹Unidad de Investigaciones y Desarrollo en Tecnología Farmacéutica (UNITEFA) – ONICET, Departamento de Ciencias Farmacéuticas, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina
²IFEC-CONICET, Depto. Farmacología Otto Orsingher, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina

Index