Chapter 4. Infectious Diseases: Antibiotic Resistance and Stewardship


Rajkumari Mazumdar¹,², Juri Saikia¹,³ and Debajit Thakur¹
¹Microbial Biotechnology Laboratory, Life Sciences Division, Institute of Advanced Study in Science and Technology (IASST), Guwahati, India
²Department of Molecular Biology and Biotechnology, Cotton University, Guwahati, India
³Department of Biotechnology, Gauhati University, Guwahati, India

Part of the book: Infectious Diseases: From Prevention to Control


Infectious diseases are illnesses caused by pathogenic microorganisms that enter our bodies from the outside. They can sometimes be caught by other people, the environment, animal contact, or insect bites. Some infections are so mild that we might not notice any symptoms, while others can be fatal. Existing and emerging infectious diseases pose significant challenges to public health outcomes around the globe. Pathogenic bacteria continue to be a severe health concern, causing many fatalities and hospitalizations yearly. Due to the development of new variants of drug-resistant pathogenic microorganisms, the treatment and immunization of infectious diseases have become even more challenging in recent years. Existing diagnostic techniques are inefficient because they lack speed and ultra-sensitivity. Therefore, novel therapeutic and diagnostic approaches are required. The primary goal of this study is to highlight current trends in antibiotic resistance as well as novel therapeutic prospects for future disease management and control advancements.

Keywords: infectious diseases, antimicrobial resistance, pathogenic bacteria, WHO, actinobacteria, antimicrobial peptides, nanoparticle


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