Chapter 32. Cholecystokinin


Aleksandra Wiechecka, Dorota Bartusik-Aebisher, and David Aebisher
Medical College of The University of Rzeszów, Rzeszów, Poland

Part of the book: The Biochemical Guide to Hormones


Cholecystokinin (CCK) is a peptide hormone that acts in both the digestive and central nervous systems. It is responsible for the intake and digestion of food, therefore it plays an important role in the human body. CCK is structurally related to gastrin, and its CCK B receptors bind it. The role of this hormone in the central nervous system is diverse. It works not only to inhibit hunger, but also to reduce anxiety and panic attacks. A receptor antagonist by blocking the sites for CCK may protect against diseases such as stomach ulcers and anxiety. The diverse functions of cholecystokinin and its receptors arouse the interest of many scientists, which is why they take part in many studies.

Keywords: cholecystokinin (CCK), pancreatic enzymes, C-terminal amino acids, hormone


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