Chapter 31. Leukotrienes

$39.50

Wiktoria Mirowska, Dorota Bartusik-Aebisher, and David Aebisher
Medical College of The University of RzeszĂłw, RzeszĂłw, Poland

Part of the book: The Biochemical Guide to Hormones

Abstract

The involvement of leukotrienes in inflammatory processes is the main factor that prompts scientists to conduct clinical trials to develop new anti-leukotriene drugs. So far, these drugs have been used in patients with mild, moderate and severe asthma as well as asthma with hypersensitivity to aspirin. They are also used in the case of nasal polyps, hypertrophic rhinitis and sinuses, urticaria, and digestive system diseases. In the future, anti-leukotriene drugs may appear in cardiology, and more specifically as an aid in the case of ischemia of tissues, including the heart muscle. Doctors place a lot of hope in them because they can contribute to the development of medicine.

Keywords: leukotrienes, T lymphocytes, erythrocytes, endothelial cells, vascular permeability, glucocorticosteroids


References


Jiang X, Nicolls MR, Tian W, Rockson SG. Lymphatic Dysfunction, Leukotrienes, and
Lymphedema. Annu Rev Physiol, 2018 Feb 10; 80:49-70.
McGinty JW, Ting HA, Billipp TE, Nadjsombati MS, Khan DM, Barrett NA, Liang HE,
Matsumoto I, von Moltke J. Tuft-Cell-Derived Leukotrienes Drive Rapid Anti helminth Immunity in the Small Intestine but Are Dispensable for Anti-protist
Immunity. Immunity, 2020 Mar 17; 52(3):528-541.e7.
Rubinstein M, Dvash E. Leukotrienes and kidney diseases. Curr Opin Nephrol Hypertens,
2018 Jan; 27(1):42-48.
Sirois P. Leukotrienes: One step in our understanding of asthma. Respir Investig, 2019 Mar;
57(2):97-110.
Tian W, Jiang X, Kim D, Guan T, Nicolls MR, Rockson SG. Leukotrienes in Tumor Associated Inflammation. Front Pharmacol, 2020 Aug 19; 11: 1289.

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