Chapter 3. Hydroxyapatite: Synthesis and Characterization

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Safia Alleg and Meriem Harkat
Laboratory of Magnetism and Spectroscopy of Solids (LM2S), Department of Physics, Badji Mokhtar Annaba University, Annaba, Algeria

Part of the book: What to Know about Hydroxyapatite

Abstract

Nanocrystalline hydroxyapatite (HAp) has been successfully used for biomedical applications during the last decades owing to its chemical similarity with natural apatite, its remarkable biocompatibility, bio[1]affinity, and bioactivity that can be related to its crystal structure. HAp is the most stable, least soluble of all calcium orthophosphates, and is one of the most promising calcium phosphate biomaterials which can be obtained from chemical reagent, natural sources, animal-like dental enamel, corals, etc. Thermally stable HAp powders have been prepared using wet chemical route and co-precipitation method from various precursors such as naturally abundant seashell waste, calcium hydroxide Ca(OH)6 and mono ammonium phosphate NH4H2PO4 as calcium and phosphate sources, respectively. The crystal structure, morphology, elemental analysis, molecular bonding, and electric properties of the synthesized HAp powders have been studied using X-ray diffraction (XRD), scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDS), Raman spectroscopy, Fourier transform infrared spectroscopy (FT-IR), and complex impedance spectroscopy. The effect of simulated body fluids immersion on the molecular bending and electric properties is also reported.

Keywords: hydroxyapatite, structure, microstructure, morphology, electric properties


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