Chapter 29. Prostate-Specific Antigen (PSA)


Halszka Wajdowicz, Dorota Bartusik-Aebisher and David Aebisher
Medical College of The University of Rzeszów, Poland

Part of the book: The Biochemical Guide to Proteins


PSA is certainly one of the most important clinical human proteins that the scientific world has been interested in for decades. As a prostatic biomarker, it allows the detection of a large number of prostate pathologies at an early stage of development thus significantly increasing the chances of recovery or survival of the patient. It should also be mentioned that thanks to the easy and cheap form of the PSA test, it also made it possible to popularize prophylaxis in men. The deepening of the knowledge of the scientific world in this field also influenced the growing awareness of the need for research among men – this is confirmed by the annual, nationwide campaign called “MOVEMBER”, which aims to make the society aware of the widespread problem of prostate cancer.

Keywords: prostate-specific antigen (PSA), peptides, N-terminal amino acids, biomarker, prostate cancer


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