Chapter 11. Platelet-Derived Growth Factor (PDGF)
Monika Błądek, Dorota Bartusik-Aebisher and David Aebisher
Medical College of The University of Rzeszów, Rzeszów, Poland
Part of the book: The Biochemical Guide to Proteins
Platelet growth factor, a glycoprotein present in several isoforms, is undoubtedly an important factor found in the human body, which is produced by a variety of cells and is widely expressed. Since its discovery the several decades ago, many different studies have been carried out, which allowed to learn about its structure, biosynthesis process and operation. The emergence of different varieties of this factor confirms that it performs many important and different functions. Platelet growth factor is still a factor that is discussed in subsequent scientific research, which is a source of new, valuable and sometimes surprising information. Undoubtedly, the knowledge about this factor will keep increasing, as it is a topic worth further attention.
Keywords: platelet-derived growth factor (PDGF), oligodendrocyte progenitor cells (OPCs), fibrosarcoma, microblastic skin tumors
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