Publish with Nova Science Publishers
We publish over 800 titles annually by leading researchers from around the world. Submit a Book Proposal Now!
Natalia Guzik, Dorota Bartusik-Aebisher and David Aebisher
Medical College of The University of Rzeszów, Poland
Part of the book: The Biochemical Guide to Proteins
Enkephalins are a group of compounds that are widely distributed in the body and fulfill their functions by stimulating opioid receptors in various parts of the body. Met-enkephalin is also known as growth factor (OGF) because it is involved in the regulation of the immune system. Metenkephalin is involved in tissue regeneration and activates the OGF receptor. The conducted research also shows the presence of metenkephalin and its precursor in the sperm head, where it acts as an endogenous mediator of sperm motility. Enkephalins are therefore compounds that have a wide range of applications, therefore they are often used as drugs in the course of many diseases.
Keywords: met-enkephalin, leu-enkephalin, amino acid, cerebrospinal fluid (CSF)
Bando, S., Nishikado, A., Hiura, N., Ikeda, S., Kakutani, A., Yamamoto, K., Kaname, N.,
Fukatani, M., Takagi, Y., Yukiiri, K., Fukuda, Y., and Nakaya, Y. (2018). Efficacy
and safety of rivaroxaban in extreme elderly patients with atrial fibrillation: Analysis
of the Shikoku Rivaroxaban Registry Trial (SRRT). J Cardiol., Feb, 71(2), 197-201.
Dou, Y., Kalmykova, S., Pashkova, M., Oghbaie, M., Jiang, H., Molloy, K. R., Chait, B.
T., Rout, M. P., Fenyö, D., Jensen, T. H., Altukhov, I., and LaCava, J. (2020). Affinity
proteomic dissection of the human nuclear cap-binding complex interactome. Nucleic
Acids Res., Oct 9, 48(18), 10456-10469.
Kainov, Y. A., and Makeyev, E. V. (2020). A transcriptome-wide antitermination
mechanism sustaining identity of embryonic stem cells. Nat Commun., Jan 17, 11(1), 361.
Lykke-Andersen, S., Rouvière, J. O., and Jensen, T. H. (2021). ARS2/SRRT: at the nexus
of RNA polymerase II transcription, transcript maturation and quality control.
Biochem Soc Trans., Jun 30, 49(3), 1325-1336.
Yin, J., Kim, S. S., Choi, E., Oh, Y. T., Lin, W., Kim, T. H., Sa, J. K., Hong, J. H., Park, S.
H., Kwon, H. J., Jin, X., You, Y., Kim, J. H., Kim, H., Son, J., Lee, J., Nam, D. H.,
Choi, K. S., Shi, B., Gwak, H. S., Yoo, H., Iavarone, A., Kim, J. H., and Park, J. B.
(2020). ARS2/MAGL signaling in glioblastoma stem cells promotes self-renewal and
M2-like polarization of tumor-associated macrophages. Nat Commun., Jun 12, 11(1), 2978.