Chapter 10. Enkephalins as Peptides Widely Distributed in the Body

Natalia Guzik, Dorota Bartusik-Aebisher and David Aebisher
Medical College of The University of Rzeszów, Poland

Part of the book: The Biochemical Guide to Proteins


Enkephalins are a group of compounds that are widely distributed in the body and fulfill their functions by stimulating opioid receptors in various parts of the body. Met-enkephalin is also known as growth factor (OGF) because it is involved in the regulation of the immune system. Met[1]enkephalin is involved in tissue regeneration and activates the OGF receptor. The conducted research also shows the presence of met[1]enkephalin and its precursor in the sperm head, where it acts as an endogenous mediator of sperm motility. Enkephalins are therefore compounds that have a wide range of applications, therefore they are often used as drugs in the course of many diseases.

Keywords: met-enkephalin, leu-enkephalin, amino acid, cerebrospinal fluid (CSF)


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