Table of Contents
Preface
Chapter 1. Neurofibromatosis Type 2: Central Nervous System Pathology
Darren Liu, BS, BA1 and Richard A. Prayson2, MD, Med
1Cleveland Clinic Lerner College of Medicine
2Cleveland Clinic Department of Anatomic Pathology
Chapter 2. Tuberous Sclerosis: Central Nervous System Pathology
Alissa Becerril1, BA and Richard A. Prayson2, MD, Med
1Cleveland Clinic Lerner College of Medicine, OH, USA
2Cleveland Clinic Department of Anatomic Pathology, Cleveland Clinic, OH, USA
Chapter 3. Neuropathologic Features of von Hippel-Lindau Syndrome
Richard A. Prayson, MD, MEd and Elizabeth E. O’Toole2, MD
Cleveland Clinic1 and MetroHealth Medical Center2, Cleveland, OH, USA
Chapter 4. Sturge-Weber Syndrome: Central Nervous System Pathology
Richard A. Prayson, MD, Med
Cleveland Clinic, Department of Anatomic Pathology, Cleveland, Ohio, USA
Chapter 5. Neuropathologic Features of Cowden Disease
Richard A. Prayson and Brigid E. Prayson
Cleveland Clinic, Cleveland, Ohio and Allegheny Health Network, Pittsburgh, PA
Chapter 6. Schwannomatosis: Central Nervous System Pathology
Aiman J. Faruqi1, BS, Mario S. Belfiglio1, BS, and Richard A. Prayson2, MD
1Cleveland Clinic Lerner College of Medicine, Cleveland Clinic, Cleveland, Ohio, USA
2Cleveland Clinic, Department of Anatomic Pathology, Cleveland Clinic, Cleveland, Ohio, USA
Chapter 7. Clinical and Pathological Aspects of Li-Fraumeni Syndrome – Focus on the Central Nervous System
Georgi Galev, MD and Richard A. Prayson, MD, Med
Cleveland Clinic Department of Anatomic Pathology, Cleveland, Ohio, USA
Chapter 8. Carney Complex: Nervous System Pathology
Maleeha F. Ahmad1 and Richard A. Prayson2 , MD
1Cleveland Clinic Lerner, College of Medicine
2Cleveland Clinic, Department of Anatomic Pathology, OH, USA
Chapter 9. Lynch Syndrome: Central Nervous System Pathology
Surabhi Tewari1 and Richard A. Prayson2
1Cleveland Clinic Lerner College of Medicine
2Department of Anatomic Pathology, Cleveland Clinic, Cleveland, Ohio
Chapter 10. Familial Retinoblastoma: Central Nervous System Pathology
Suzie Kim1, BS, and Richard A. Prayson2, MD Med
1Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio, USA
2Cleveland Clinic, Department of Anatomic Pathology, Cleveland, Ohio, USA
Chapter 11. Fanconi Anemia: A Neuropathologic Perspective
Joshua L Tidd1, Samantha J Stallkamp Tidd2 and Richard A. Prayson3, MD
1Northeast Ohio Medical University, Rootstown, OH, United States of America
2Cleveland Clinic Lerner College of Medicine, Cleveland, OH, United States of America
3Cleveland Clinic Lerner College of Medicine and Department of Anatomic Pathology, Cleveland Clinic, United States of America
Chapter 12. Clinicopathologic Review of the Familial Paraganglioma Syndromes
Samantha J Stallkamp Tidd1, BS, Joshua L. Tidd2, BS, and Richard A. Prayson3, MD, Med
1Cleveland Clinic Lerner College of Medicine, Cleveland, OH, USA
2Northeast Ohio Medical University, Rootstown, OH, USA
3Cleveland Clinic, Department of Anatomic Pathology, Cleveland Clinic, USA
Chapter 13. Familial Melanoma-Astrocytoma Syndrome
Narendra Bhattarai, MD and Richard A. Prayson, MD, Med
Cleveland Clinic Department of Anatomic Pathology, Clevelend, Ohio, USA
Chapter 14. Neuropathologic Findings in Familial Adenomatous Polyposis Syndrome
Hailey L. Gosnell, MD and Richard A. Prayson, MD
Cleveland Clinic, Department of Anatomic Pathology, Cleveland, Ohio, USA
Chapter 15. BAP1 Tumor Predisposition Syndrome: Central Nervous System Pathology
Maeve Pascoe1, BS and Richard A. Prayson2, MD, Med
1Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio, USA
2Cleveland Clinic Department of Anatomic Pathology, Cleveland, Ohio, USA
Chapter 16. ELP1-Medulloblastoma Syndrome
Mario-Cyriac Tcheukado1, BS, Derrick Obiri-Yeboah1, BS and Richard A. Prayson2,1, MD, Med
1Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio, USA
2Cleveland Clinic, Department of Anatomic Pathology Cleveland, Ohio, USA
Chapter 17. Nevoid Basal Cell Carcinoma Syndrome: Neuropathologic Features
Derrick Obiri-Yeboah1, BS, Mario-Cyriac Tcheukado1, BS, and Richard A. Prayson2, MD, Med
1Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio, USA
2Cleveland Clinic, Department of Anatomic Pathology Cleveland, Ohio, USA
Chapter 18. Constitutional Mismatch Repair Deficiency Syndrome: Central Nervous System Pathology
Lauren E. Heusinkveld1, BS and Richard A. Prayson2, MD, Med
1Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio, USA
2Department of Anatomic Pathology, Cleveland Clinic, Cleveland, Ohio, USA
Chapter 19. Rhabdoid Tumor Predisposition Syndrome: Pathology of a Heritable Syndrome Primarily Affecting the Central Nervous System
Stephanie Njemanze1, BA, BS and Richard A. Prayson2, MD, Med
1Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio, USA
2Cleveland Clinic Department of Anatomic Pathology, Cleveland, Ohio, USA
Chapter 20. DICER1 Syndrome: A Neuro-Clinicopathologic Review
Kiran A. Vaidya1, BA and Richard A. Prayson2, MD, Med
1Cleveland Clinic, Lerner College of Medicine, Cleveland, Ohio, USA
2Cleveland Clinic, Department of Anatomic Pathology,
Cleveland, Ohio, USA
Chapter 21. Pituitary Gland and Systemic Pathology of Multiple Endocrine Neoplasia Type I (MEN1)
Dhananjay Prakash1, BS, MS, Precious C. Oyem2, BA and Richard A. Prayson3, MD, Med
1Case Western Reserve University
2Cleveland Clinic Lerner College of Medicine,
3Department of Anatomic Pathology Cleveland Clinic, USA
Chapter 22. Noonan Syndrome: Central Nervous System Manifestations
Precious C. Oyem1, BA, Dhananjay Prakash2, BS, MS, and Richard A. Prayson3,1, MD
1Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio, USA
2Case Western Reserve University, Cleveland, Ohio, USA
3Cleveland Clinic Department of Anatomic Pathology, Cleveland, Ohio, USA
Chapter 23. Neuropathologic Findings in L-2-Hydroxyglutaric Aciduria
Christel M. Kinkopf1 and Richard A. Prayson2 , MD
1Ohio Heritage College of Osteopathic Medicine, Warrensville Heights, OH, USA
2Cleveland Clinic, Department of Anatomic Pathology, Cleveland, Ohio, USA
Index