Cellular and Molecular Mechanisms of Honey Wound Healing

Elia Ranzato and Simona Martinotti (Editors)
DiSIT, University of Piemonte Orientale, Alessandria, Italy

Series: Food Science and Technology
BISAC: TEC012000

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Honey has a long and interesting history. Since Biblical times and before, it has been known to have beneficial health effects and it is still widely used in “folk medicine”. Recently, the therapeutic virtues of honey have been rediscovered by the medical profession and are gaining acceptance for treating ulcers, wounds and other surface infections. Wound healing is of great relevance for skin medicine and a particular focus is set on natural compounds. Furthermore, reports show that honey has been successfully used on infections that were unresponsive to standard antiseptic and antibiotic therapy.

Honey has been renowned since ancient times for skin care, dermatologic, and wound-healing properties. Its physicochemical properties make it perfect for wound dressing, providing moisture, contrasting infections, reducing inflammation, oedema and exudation, and preventing bandages from sticking to wounds. Honey is increasingly used as a wound dressing in clinical settings, but the relationships between its healing properties and the wound repair mechanism are still largely unexplored. In spite of a vast amount of literature about the clinical uses of honey, the subjacent mechanisms of action are still largely obscure. In a number of cases, beneficial effects have been ascribed to antiseptic properties, but accumulating data suggests the involvement of other specific physiological mechanisms that this book explores. (Imprint: Nova Biomedical)

Preface (pp. vii-vix)
Elia Ranzato and Simona Martinotti (DiSIT, University of Piemonte Orientale, Alessandria, Italy)

Chapter 1. Honey’s Healing History
Simona Martinotti and Elia Ranzato (DiSIT, University of Piemonte Orientale, Alessandria, Italy)

Chapter 2. The Clinical Application of Medical Honey in an Everchanging World
Natasha Old (Tweed Hospital, NSW, Australia)

Chapter 3. Wound Contraction Effect and Antimicrobial Properties of Honey on Burn Wounds
Khoo Yan Teng and Ahmad Sukari Halim (Plastic Surgeon, Department of Plastic and Reconstructive Surgery, Hospital Raja Permaisuri Bainun, Perak, Malaysia)

Chapter 4. Efficacy of Natural Honey in the Management of Diabetic Foot Ulcers
Hashim Mohamed (Weill Cornell Medical College, Qatar)

Chapter 5. The Present and the Potential of Manuka Honey in Dermal Regenerative Medicine
Daniel Abebayehu, Andrew J. Spence and Scott A. Sell (Department of Biomedical Engineering, Virginia Commonwealth University, Virginia, USA)

Chapter 6. Manuka Honey: It’s Role in Second Intention Wound Healing in Horses
Andrew Dart and Josephine Meagher (Research and Clinical Training Unit, University Veterinary Teaching Hospital, The University of Sydney, Camden, NSW, Australia)

Chapter 7. Analgesic and Anti-Inflammatory Effects of Honey: The Role of Adenosine Receptors
Bamidele Victor Owoyele and Margaret O. Oladeinde (Department of Physiology, University of Ilorin, llorin, Nigeria)

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