Caspases: Roles and Significance in Cell Death and Disease

Jeffrey Warren (Editor)

Series: Cell Biology Research Progress
BISAC: SCI017000

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Volume 10

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Volume 2

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Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick

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Caspases are proteases that are responsible for the initiation and execution of cell death pathways in developmental, inflammatory and pharmacological paradigms. Caspase activity is required for the execution of apoptotic cell death through the proteolytic cleavage of approximately one thousand substrates that result in the apoptotic phenotype. This book provides new research and discusses the roles and significance caspases have in cell death and disease. (Imprint: Nova)

Preface

Chapter 1. Caspases: A Driver In Programmed Cell Death
Osim Aquatar, Pooja R. Mogarkar, Stephy Rangari, and Tanvir Arfin (Environmental Materials Division, CSIR-NEERI, Nehru Marg, Nagpur, India, and others)

Chapter 2. Caspases Importance in Cell Death and Disease
Pooja R. Mogarkar, Osim Aquatar, Stephy Rangari, and Tanvir Arfin (Environmental Materials Division, CSIR-NEERI, Nehru Marg, Nagpur, India, and others)

Chapter 3. The Role of Executioner Caspases in Cancer Formation and Maintenance
Marwan Hamed, Sharif Zaher and Gavin P. McStay (Department of Life Sciences, New York Institute of Technology, NY, USA)

Chapter 4. The Unknown Caspase: The Role of Caspase-14 in Cell Death and Disease
C. M. Neophytou, I. Theofilou and A. I. Constantinou (Department of Biological Sciences, Faculty of Pure and Applied Sciences, University of Cyprus, Nicosia, Cyprus)

Chapter 5. Differential Regulation of Caspases in CNS
Kyoungjoo Cho and Gyung Whan Kim (Neurology, College of Medicine, Yonsei University, Seoul Korea)

Index

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