Cardiac Remodeling: Molecular Mechanisms, Treatment and Clinical Implications


Jerald Sherman (Editor)

Series: Cardiology Research and Clinical Developments
BISAC: MED010000

Cardiovascular diseases are the leading cause of death in almost 40% of patients suffering from end stage renal disease (ESRD). Cardiomyopathy and ischemic heart disease are the most frequent causes of cardiac death. The risk of cardiovascular mortality in dialysis patients is 10 to 20 times greater than the general population, particularly in younger patients, taking into account that the relative risk decreases with age.

Left ventricular hypertrophy (LVH) is the most common cardiac abnormality in chronic kidney disease (CKD), and the survival risk ratio in such patients is independent. This book examines the molecular mechanisms, treatments and clinical implication of cardiac remodeling. The first chapter discusses risk factors for cardiovascular disease in patients on continuous ambulatory peritoneal dialysis. The following chapters examine the impacts tropomyosin, vitamin D, and coffee have on cardiac remodeling.
(Imprint: Nova Biomedical)

Table of Contents

Table of Contents


Chapter 1
Risk Factors for Cardiovascular Disease in Patients on Continuous Ambulatory Peritoneal Dialysis
(Damir Rebiæ, Velma Rebiæ, Clinic for Nephrology, University Clinical Center of Sarajevo, Bosnia and Herzegovina, and others)

Chapter 2
Tropomyosin: An Effector of Cardiac Remodeling
(David F. Wieczorek, Department of Molecular Genetics, Biochemistry, and Microbiology, University of Cincinnati Medical Center, Cincinnati, Ohio, USA)

Chapter 3
Impact of Vitamin D System on Ventricular Remodeling
(Claudia Kusmic, Nicoletta Vesentini and Cristina Barsanti, Institute of Clinical Physiology, CNR, Pisa, Italy, and others)

Chapter 4
Effects of Coffee Polyphenols on Myocardial Remodeling
(Jun-ichi Suzuki, Department of Advanced Clinical Science and Therapeutics, The University of Tokyo, Japan)



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