Capillary Electrophoresis in the Early Twenty-First Century: New Trends and Relevant Applications

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Series: Analytical Chemistry and Microchemistry
BISAC: SCI013060

Capillary electrophoresis (CE) comprises a family of related separation techniques in which an electric field is used to achieve the separation of components in a mixture. One of the key features of CE is the simplicity of the instrumentation required, and today, these techniques have become powerful analytical tools for high efficiency separation, and the identification of a variety of ionic and neutral compounds.

Moreover, the versatility of CE operational modes (capillary zone electrophoresis, micellar electrokinetic capillary chromatography, capillary electrochromatography, capillary isoelectric focusing, isotachophoresis, non-aqueous capillary electrophoresis, etc.) and detection systems (ultraviolet, fluorescence, amperometric, mass spectrometry…) make CE useful for applications in many fields such as environmental, food, pharmaceutical, and forensic analysis. The typcial drawback of CE techniques, based on their low sensitivity when dealing with conventional UV-detection, due to their short detection pathways and the short sample volume introduced into the capillary, has been largely resolved not only by using more sensitive detectors like fluorescence, amperometric, or mass spectrometry, but by the employment of both off-line and on-line enrichment procedures.

The aim of this present book is to address the state-of-the art of capillary electrophoresis techniques within this early twenty-first century, by reviewing new trends and the most relevant applications described in the literature. Uses in fields such as food, environmental, forensic and biological analysis are addressed by means of relevant application. The scope of this book is intentionally broad and is aimed at worldwide analytical laboratories, both public and private, at acadamic institutions, as well as researchers.
(Imprint: Nova)

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Table of Contents

Table of Contents

Preface

Chapter 1. The Role of Capillary Zone Electrophoresis in Food and Environmental Analysis
(Oscar Núñez and Xavier Subirats, Department of Chemical Engineering and Analytical Chemistry, University of Barcelona, Barcelona, Spain, and others)

Chapter 2. The Role of Capillary Electrophoresis in the Chemometric Characterization of Food Products
(Sonia Sentellas and Javier Saurina, Department of Chemical Engineering and Analytical Chemistry, University of Barcelona, Barcelona, Spain, and others)

Chapter 3. Capillary Electrophoresis in Forensic Analysis
(Maykel Hernández-Mesa and Carmen Cruces-Blanco, Department of Analytical Chemistry, University of Granada, Granada, Spain)

Chapter 4. Advances in the Chiral Analysis of Drugs by Capillary Electrophoresis
(Elena Sánchez-López and María Luisa Marina, Department of Analytical Chemistry, Physical Chemistry and Chemical Engineering, University of Alcalá, Alcalá de Henares, Madrid, Spain)

Chapter 5. New Trends in Capillary Electrochromatography Techniques
(Chiara Fanali and Giovanni D’Orazio, Unit of Food Science and Nutrition, Department of Medicine, Università Campus Bio-Medico di Roma, Rome, Italy, and others)

Chapter 6. Micellar and Microemulsion Electrokinetic Capillary Chromatography as Surrogate Models for Lipophilicity and Biological Activity
(Xavier Subirats and Oscar Núñez, Department of Chemical Engineering and Analytical Chemistry, University of Barcelona, Barcelona, Spain, and others)

Chapter 7. Capillary Electrophoresis in the Pharmaceutical and Biotech Industry
(Ewoud van Tricht, Lars Geurink and Cari E Sänger – van de Griend, Analytical Development, Janssen Vaccines and Prevention BV, Leiden, Netherlands, and others)

Index

Additional Information

Keywords: Capillary Electrophoresis, Capillary Electrophoresis-Mass Spectrometry, Food Analysis, Environmental Analysis, Forensic Analysis, Biological Analysis, Pharmaceutical Analysis

Audience: Academic Institutions.
Private and public institutions doing research in chemistry, biochemistry, food analysis, environmental analysis.
Researchers in the fields of chemistry, biochemistry, and in environmental, food, forensic, and bioanalytical analysis

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